From Gene to Protein: Information Transfer in Normal and Abnormal Cells

Author: Russell   Thomas  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780323143707

P-ISBN(Paperback): 9780126044508

P-ISBN(Hardback):  9780126044508

Subject: Q1 General Biology

Language: ENG

Access to resources Favorite

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Description

Miami Winter Symposia, Volume 16: From Gene to Protein: Information Transfer in Normal and Abnormal Cells presents the expression and processing of genetic information at the levels of both proteins and nucleic acids. This book deals with the reassembly and mobilization of genetic information.

Organized into 105 chapters, this volume begins with an overview of the discovery of the double helix and the search for the genetic code and the three-dimensional structure of protein. This text then examines the molecular mechanism by which steroid hormones regulate specific gene expression. Other chapters consider the possible hazards inherent to hybrid DNA technology. This book discusses as well the various problems of gene control in higher organisms, which are illustrated by the changes that occur in the hemoglobin of mammals. The final chapter deals with the characterization of adenovirus-2 mRNAs.

This book is a valuable resource for biochemists, genetic engineers, enzymologists, scientists, geneticists, and molecular biologists.

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Table of Contents

pp.:  6 – 20

PREFACE

pp.:  24 – 26

Chapter 2. The Ovomucoid Gene: Organization, Structure, and Regulation

pp.:  40 – 80

Chapter 3. Structural Orgsnization and Expression of Ovolbumin and Related Chicken Genes

pp.:  80 – 108

Chapter 4. An Endonuclease-Sensitive Region in Simian Virus 40 Chromatin

pp.:  108 – 124

Chapter 5. Expression of Cloned Viral and Chromosomal Plasmid- Linked DNA in Cognate Host Cells

pp.:  124 – 158

Chapter 6. The Arrangement, Rearrangement, and Origin of Immunoglobulin Genes

pp.:  158 – 174

Chapter 7. The Structure and Expression of Normal and Abnormal Globin Genes

pp.:  174 – 192

Chapter 8. Genomic Clones from Unfractionated DNA

pp.:  192 – 212

Chapter 9. The Processing of Messenger RNA and the Determination of Its Relative Abundance

pp.:  212 – 232

Chapter 10. Steps in Processing of mRNA: Implications for Gene Regulation

pp.:  232 – 254

Chapter 11. 5'-Capping and Eukaryotic mRNA Function

pp.:  254 – 270

Chapter 12. Splice Patterns of Adenovirus and Adenovirus-SV40 Mosaic RNA's

pp.:  270 – 286

Chapter 13. Processing of Bacteriophage T7 RNAs by RNase III

pp.:  286 – 296

Chapter 14. Regulation of Promoter Selection by RNA Polymerases

pp.:  296 – 322

Chapter 15. Synthesis and Maturation of Transmembrane Viral Glycoproteins

pp.:  322 – 346

Chapter 16. The Control of Protein Synthesis in Rabbit Reticulocyte Lysates

pp.:  346 – 372

Chapter 17. Determinants in Protein Topology

pp.:  372 – 386

Chapter 18. Precursors in the Biosynthesis of Insulin and Other Peptide Hormones

pp.:  386 – 404

Chapter 19. Biosynthesis and Processing of Glycoproteins

pp.:  404 – 432

Chapter 20. The Enzymatic Conversion of Membrane and Secretory to Glycoproteins

pp.:  432 – 450

Chapter 21. Oligosaccharide Processing during Glycoprotein Biosynthesis

pp.:  450 – 458

Chapter 22. Structural Basis of the Regulation of Galactosyltransferase

pp.:  458 – 474

Chapter 23. Specificity Considerations Relevant to Protein Kinase Activation and Function

pp.:  474 – 488

Chapter 24. The Role of Protein Phosphorylation in the Coordinated Control of Intermediary Metabolism

pp.:  488 – 508

Chapter 25. Protein Phosphatase C: Properties, Specificity, and Structural Relationship to a Larger Holoenzyme

pp.:  508 – 526

Chapter 26. Regulation of Pyruvate Dehydrogenase by Phosphorylation/ Dephosphorylation

pp.:  526 – 546

Chapter 27. Allosteric Control of E. coli Glutamine Synthetase is Mediated by a Bicyclic Nucleotidylation Cascade System

pp.:  546 – 570

Chapter 28. Poly(ADP-Ribose) and ADP-Ribosylation of Proteins

pp.:  570 – 592

Chapter 29. Identification of Two Collagen RNAs Larger than α1 and α2 Collagen mRNAs which Are Decreased in Transformed Cells

pp.:  592 – 593

Chapter 30. Processing of RNA in Bacteria

pp.:  593 – 594

Chapter 31. The Protein Moieties of the Nonpolysomal Cytoplasmic (Free) mRNP Complexes of Embryonic Chicken Muscle

pp.:  594 – 595

Chapter 32. Complex Oligosaccharides Assembled on Lipid Intermediates: Studies with UDP-N-Acetylglucosamine and GDP-Mannose

pp.:  595 – 596

Chapter 33. Is There a Different Mode of DNA Synthesis in Normal and Transformed Human Diploid Fibroblasts?

pp.:  596 – 597

Chapter 34. A study of DNA region coding for initiation of precursor rRNA Transcription in Lytechinus variegatus

pp.:  597 – 598

Chapter 35. A Lectin Resistant Variant of Mouse Fibroblasts with Altered Cell Surface Galactose

pp.:  598 – 599

Chapter 36. Alterations in the Rate of Protein Synthesis of Polysomes Extracted from Fibroblasts of Patients with Duchenne Muscular Dystrophy and Carriers of the Disease

pp.:  599 – 600

Chapter 37. Biosynthesis of the Small Nuclear RNAs in a Cell-Free System from Mouse Myeloma Cells

pp.:  600 – 601

Chapter 38. A Shared Control Mechanism for Regulation of Adenovirus and SV40 Gene Expression

pp.:  601 – 602

Chapter 39. In Vitro Synthesis of Virus-Specific RNA Using Transcriptional Complex Isolated from Adenovirus-Infected Cells

pp.:  602 – 603

Chapter 40. Gene Expression of Mammalian Lens Tissue: Coexistence and Properties of Poly(A)-Containing and Poly(A)-Lacking 10S and 14S mRNA Species

pp.:  603 – 604

Chapter 41. Gene Expression of Mammalian Lens Tissue: Is Lens mRNA Bicistronic?

pp.:  604 – 605

Chapter 42. The Expression of á-Fetoprotein Gene in Normal and Neoplastic Rat Liver

pp.:  605 – 606

Chapter 43. Nuclear Phosphoprotein Phosphatase from Calf Liver

pp.:  606 – 607

Chapter 44. Chemically Induced Gene Expression: The Role of Histone Hyperacetylation in Transformation by SV40 Minichromatin

pp.:  607 – 608

Chapter 45. Transcription of the Histone mRNA Precursor during the Cell Cycle

pp.:  608 – 609

Chapter 46. Characterization of a Cytoplasmic Poly(A)-Protein Complex: Endproduct or Byproduct of Messenger RNA Metabolism?

pp.:  609 – 610

Chapter 47. Factors which Influence the Nα-Acetylation of ACTH and Fragments of ACTH

pp.:  610 – 611

Chapter 48. Instability of Higher Plant Chromosomal DNA Molecularly Cloned in E. coli via Recombinant Plasmids

pp.:  611 – 612

Chapter 49. Translation of Endogenous Non-IgG and IgG Messenger RNA in Human Leukemic Plasma Cells after Treatment with Several Alkylating Agents

pp.:  612 – 613

Chapter 50. The in situ Phosphorylation of the á-Subunit of eIF-2 in Reticulocyte Lysates Inhibited by Heme Deficiency, dsRNA, GSSG, or the Heme-Regulated Inhibitor

pp.:  613 – 614

Chapter 51.Purification of Arginyl- and Lysyl-tRNA Synthetases from Rat Liver: Evidence of Glycoproteins

pp.:  614 – 615

Chapter 52. Mammalian Cell Nuclear RNA Ligase Activity

pp.:  615 – 616

Chapter 53. Multiple Forms of alu Globulin in the Rat Studied in Vivo and in Primary Cultures of Adult Hepatocytes

pp.:  616 – 617

Chapter 54. Biosynthesis of Lysosomal Enzymes in Diploid Human Fibroblasts

pp.:  617 – 618

Chapter 55. Isolation and Partial Characterization of β-like Globin Genes from Total Genomic Goat DNA

pp.:  618 – 619

Chapter 56. Regulation of Metallothionein Synthesis in Cultured Mammalian Cells: Induction, Deinduction, and Superinduction

pp.:  619 – 620

Chapter 57. A Class of Highly Repeated DNA Sequences Ubiquitous to the Human Genome

pp.:  620 – 621

Chapter 58. Regulation of HMG-CoA Reductase and Reductase Kinase by Reversible Phosphorylation

pp.:  621 – 622

Chapter 59. Structure and Expression of the Alpha Fetoprotein Gene

pp.:  622 – 623

Chapter 60. Control of eIF-2 Phosphorylation in Rabbit Reticulocyte Lysate

pp.:  623 – 624

Chapter 61. Organization of Immunoglobulin Kappa Light Chain Genes in Germ Line and Somatic Cells

pp.:  624 – 625

Chapter 62. Cloning of Fragments of the Sea Urchin Histone Gene Cluster with SV40 DNA as a Vector

pp.:  625 – 626

Chapter 63. Regulation by Metabolites of Inactivating and Additional Phosphorylation Reactions in the Pig Heart Pyruvate Dehydrogenase Complex

pp.:  626 – 627

Chapter 64. Cyclic AMP Stimulation of Ribosomal Phosphoprotein Phosphatase Activity

pp.:  627 – 628

Chapter 65. Unusual Genome Organization of Neurospora crassa

pp.:  628 – 629

Chapter 66. Cloning and Characterization of Alleles of the Natural Ovalbumin Gene Created by Mutations in the Intervening Sequences

pp.:  629 – 630

Chapter 67. Differential Influence of mRNA Cap Metabolism on Protein Synthesis in Differentiating Embryonic Chick Lens Cells

pp.:  630 – 631

Chapter 68. Molecular Studies of Retrodifferentiation Phenomena in Proliferation-Competent Adult Hepatocyte Cultures

pp.:  631 – 632

Chapter 69. Role of Protein Synthesis in the Replication of the "Killer Virus" of Yeast

pp.:  632 – 633

Chapter 70. Effects of the Catalytic Subunit of Protein Kinase II from Reticulocytes and Bovine Heart Muscle on Protein Phosphorylation and Protein Synthesis in Reticulocyte Lysates

pp.:  633 – 634

Chapter 71. Functional Heterogeneity in the RNAs of TYMV Virions

pp.:  634 – 635

Chapter 72. Subcellular Distribution of SV40 T Antigen Species in Various Cell Lines

pp.:  635 – 636

Chapter 73. Hormonal Regulation of Protein Biosynthesis in Rat Epididymal Fat Cells: Stimulation by Insulin, Inhibition by Fasting, and Permissive Effects of Adrenal Glucocorticoids

pp.:  636 – 637

Chapter 74. Reversal of Posttranslational Tyrosylation of Tubulin

pp.:  637 – 638

Chapter 75. Salt-Dependent Transcriptional Specificity of T7 RNA Polymerase

pp.:  638 – 639

Chapter 76. Differential Sensitivity of Inhibition of Cyclic AMP Phosphodiesterase in the Thymus during Murine Leukemogenesis

pp.:  639 – 640

Chapter 77. In Vivo Subnuclear Distribution of Larger than Tetrameric Polyadenosine Diphosphoribose in Rat Liver

pp.:  640 – 641

Chapter 78. Processing and Transport of RNA following Mitogenic Stimulation of Human Lymphocytes

pp.:  641 – 642

Chapter 79. Identification of Drosophila 2S rRNA as the 3'-Part of 5.8S rRNA

pp.:  642 – 643

Chapter 80. Facilitation by Pyrimidine Nucleosides and Hypoxanthine of MNNG Mutagenesis in Chinese Hamster Cells

pp.:  643 – 644

Chapter 81. Noncoding Inserts in Hemoglobin and Simian Virus 40 Genes Are Bounded by Self-Complementary Regions

pp.:  644 – 645

Chapter 82. A Variant of Polyoma Virus Altered in Its Processing of Late Viral RNA

pp.:  645 – 646

Chapter 83. Protease-Mediated Morphological Changes Induced by Treatment of Transformed Chick Fibroblasts with a Tumor Promoter: Evidence for Direct Catalytic Involvement of Plasminogen Activator

pp.:  646 – 647

Chapter 84. Recovery of a Transforming Virus from AKR Mouse Tumor Tissue by DNA Transfection

pp.:  647 – 648

Chapter 85. Synthesis and Posttranslational Modification of Retrovirus Precursor Polyproteins Encoded by gag and env Genes

pp.:  648 – 649

Chapter 86. Avian Myeloblastosis Virus (AMV) Linear Duplex DNA: In Vitro Enzymatic Synthesis and Structural Organization Analysis

pp.:  649 – 650

Chapter 87. Studies on the DNA-Directed in Vitro Synthesis of Bacterial Elongation Factor TU

pp.:  650 – 651

Chapter 88. In Vitro Transcription of Ad2 DNA by Eukaryotic RNA Polymerases II. I. Kinetics of Formation of Stable Binary Complexes at Specific Sites

pp.:  651 – 652

Chapter 89. Characterization of Human Fetal y Globin DNA

pp.:  652 – 653

Chapter 90. Phosphorylation and Inactivation of Glycogen Synthase by a Ca+± CDR-Dependent Kinase

pp.:  653 – 654

Chapter 91. A Polypeptide in Initiation Factor Preparations That Recognizes the 5'-Terminal Cap in Eukaryotic mRNA

pp.:  654 – 655

Chapter 92. Location and Sequence of a Putative Promoter for the  Gene of Bacteriophage S13

pp.:  655 – 656

Chapter 93. Regulation of Protein Synthesis: Role of NAD+ and Sugar Phosphates in Lysed Rabbit Reticulocytes

pp.:  656 – 657

Chapter 94. The Effect of Cortisol on Glucocorticoid "Resistant" Thymocytes

pp.:  657 – 658

Chapter 95. The Effects of Streptococcus pneumoniae Infection on Hepatic Messenger RNA Production

pp.:  658 – 659

Chapter 96. Identification of Putative Precursors of Ovalbumin and Ovomucoid Messenger RNAs

pp.:  659 – 660

Chapter 97. Purification of mRNA Guanylyl Transferase from HeLa Cells

pp.:  660 – 661

Chapter 98. Emergence of Resistance to Glucocorticoid Hormones in Cancer Cells: Detection of Differences in Proteins Synthesized by Glucocorticoid-Sensitive and -Resistant Mouse P1798 Lymphosarcoma Cells

pp.:  661 – 662

Chapter 99. Complexity and Diversity of Polysomal and Informosomal mRNA from Chinese Hamster Cells

pp.:  662 – 663

Chapter 100. Characterization of a Virion-Associated RNA Polymerase from Killer Yeast

pp.:  663 – 664

Chapter 101. In Vitro Transcription of Ad2 DNA by Eukaryotic RNA Polymerases II. II. Transcription from Stable Binary Complexes

pp.:  664 – 665

Chapter 102. Mouse Fetal Hemoglobin Synthesis in Murine Erythroleukemic Cells

pp.:  665 – 666

Chapter 103. Spectroscopic Probes for Study of Gene Transcription

pp.:  666 – 667

Chapter 104. Positive Transcriptional Control of Inducible Galactose Pathway Enzymes in Yeast

pp.:  667 – 668

Chapter 105. Localization and Characterization of the 5' End of Adenovirus-2 Fiber mRNA

pp.:  668 – 669

The users who browse this book also browse


No browse record.