Challenges and Opportunities of Next-Generation Sequencing for Biomedical Research ( Volume 89 )

Publication series :Volume 89

Author: Rees   Mark  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780123982735

P-ISBN(Paperback): 9780123942876

P-ISBN(Hardback):  9780123942876

Subject: Q343.1 gene theory

Language: ENG

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Description

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This volume features articles on Challenges and Opportunities of Next-Generation Sequencing for Biomedical Research.

  • Covers reviews of methodology and research in all aspects of protein chemistry
  • Brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics

Chapter

Front Cover

pp.:  1 – 4

Copyright

pp.:  5 – 6

Contents

pp.:  6 – 8

Preface

pp.:  8 – 12

Chapter One: Next Generation Sequencing Methodologies - An Overview

pp.:  12 – 38

Chapter Two: Next Generation Sequencing in the Clinical Domain: Clinical Advantages, Practical, and Ethical Challenges

pp.:  38 – 76

Chapter Three: Opportunities and Challenges for Genome Sequencing in the Clinic

pp.:  76 – 96

Chapter Four: Polymorphisms in Neuropsychiatric and Neuroinflammatory Disorders and the Role of Next Generation Sequencing in Early Diagnosis and Treatment

pp.:  96 – 128

Chapter Five: Structural Modelling Pipelines in Next Generation Sequencing Projects

pp.:  128 – 180

Author Index

pp.:  180 – 202

Subject Index

pp.:  202 – 210

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