Description
The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain.
Review for Placebo and Pain: “This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues.--Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School
- Contains historical aspects of the placebo effect
- Discusses biological and psychological mechanisms of placebo analgesic responses
- Reviews implications of the placebo effect for clinical research and pain management
- Includes methodological and ethical aspects of the placebo effect
Chapter
Chapter
2 - Neurochemistry of Placebo Analgesia: Opioids, Cannabinoids and Cholecystokinin
pp.:
22 – 28
Chapter
3 - Placebo Analgesia in Rodents
pp.:
28 – 38
Chapter
4 - Molecular Mechanisms of Placebo Responses in Humans
pp.:
38 – 50
Chapter
5 - How does EEG Contribute to Our Understanding of the Placebo Response?: Insights from the Perspective of Bayesian Inference
pp.:
50 – 58
Chapter
6 - Spinal Mechanisms of Placebo Analgesia and Nocebo Hyperalgesia: Descending Inhibitory and Facilitatory Influences
pp.:
58 – 66
Chapter
7 - Spinal and Supraspinal Mechanisms of Placebo Analgesia
pp.:
66 – 86
Chapter
8 - Positive and Negative Emotions and Placebo Analgesia
pp.:
86 – 96
Chapter
9 - Placing Placebo in Normal Brain Function with Neuroimaging
pp.:
96 – 102
Chapter
10 - Brain Predictors of Individual Differences in Placebo Responding
pp.:
102 – 116
Chapter
11 - Placebo Responses, Antagonistic Responses, and Homeostasis
pp.:
116 – 128
Chapter
12 - Placebo Analgesia, Nocebo Hyperalgesia, and Acupuncture
pp.:
128 – 140
Chapter
13 - The Relevance of Placebo and Nocebo Mechanisms for Analgesic Treatments
pp.:
140 – 150
Chapter
14 - How Placebo Responses are Formed: From Bench to Bedside
pp.:
150 – 162
Chapter
15 - Methodologic Aspects of Placebo Research
pp.:
162 – 172
Chapter
16 - Balanced Placebo Design, Active Placebos, and Other Design Features for Identifying, Minimizing and Characterizing the Placebo Response
pp.:
172 – 188
Chapter
17 - Psychological Processes that can Bias Responses to Placebo Treatment for Pain
pp.:
188 – 196
Chapter
18 - Against ‘Placebo.’ The Case for Changing our Language, and for the Meaning Response
pp.:
196 – 202
Chapter
19 - Placebo Effects in Complementary and Alternative Medicine: The Self-Healing Response
pp.:
202 – 216
Chapter
20 - Conceptualizations and Magnitudes of Placebo Analgesia Effects Across Meta-Analyses and Experimental Studies
pp.:
216 – 228
Chapter
21 - The Contribution of Desire, Expectation, and Reduced Negative Emotions to Placebo Anti-Hyperalgesia in Irritable Bowel Syndrome
pp.:
228 – 240
Chapter
22 - The Wound that Heals: Placebo, Pain and Surgery
pp.:
240 – 248
Chapter
23 - What are the Best Placebo Interventions for the Treatment of Pain?
pp.:
248 – 256
Chapter
24 - How Communication between Clinicians and Patients may Impact Pain Perception
pp.:
256 – 270
Chapter
25 - Nocebos in Daily Clinical Practice: The Potential Side Effects of the Treatment Context and the Patient–Doctor Interaction on Pain in Clinical Populations
pp.:
270 – 280
Chapter
26 - The Potential of the Analgesic Placebo Effect in Clinical Practice – Recommendations for Pain Management
pp.:
280 – 290
Chapter
27 - Placebo and Nocebo: Ethical Challenges and Solutions
pp.:
290 – 300
Color Plates
pp.:
306 – 322