Placebo and Pain :From Bench to Bedside

Publication subTitle :From Bench to Bedside

Author: Colloca   Luana;Flaten   Magne Arve;Meissner   Karin  

Publisher: Elsevier Science‎

Publication year: 2013

E-ISBN: 9780123979315

P-ISBN(Paperback): 9780123979285

P-ISBN(Hardback):  9780123979285

Subject: R971 nervous system medication

Language: ENG

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Description

The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain.

Review for Placebo and Pain: “This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues.”--Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School

  • Contains historical aspects of the placebo effect 
  • Discusses biological and psychological mechanisms of placebo analgesic responses
  • Reviews implications of the placebo effect for clinical research and pain management
  • Includes methodological and ethical aspects of the placebo effect

Chapter

Front Cover

pp.:  1 – 4

Copyright

pp.:  5 – 6

Contents

pp.:  6 – 10

Preface

pp.:  10 – 12

Contributors

pp.:  12 – 14

Chapter 2 - Neurochemistry of Placebo Analgesia: Opioids, Cannabinoids and Cholecystokinin

pp.:  22 – 28

Chapter 3 - Placebo Analgesia in Rodents

pp.:  28 – 38

Chapter 4 - Molecular Mechanisms of Placebo Responses in Humans

pp.:  38 – 50

Chapter 5 - How does EEG Contribute to Our Understanding of the Placebo Response?: Insights from the Perspective of Bayesian Inference

pp.:  50 – 58

Chapter 6 - Spinal Mechanisms of Placebo Analgesia and Nocebo Hyperalgesia: Descending Inhibitory and Facilitatory Influences

pp.:  58 – 66

Chapter 7 - Spinal and Supraspinal Mechanisms of Placebo Analgesia

pp.:  66 – 86

Chapter 8 - Positive and Negative Emotions and Placebo Analgesia

pp.:  86 – 96

Chapter 9 - Placing Placebo in Normal Brain Function with Neuroimaging

pp.:  96 – 102

Chapter 10 - Brain Predictors of Individual Differences in Placebo Responding

pp.:  102 – 116

Chapter 11 - Placebo Responses, Antagonistic Responses, and Homeostasis

pp.:  116 – 128

Chapter 12 - Placebo Analgesia, Nocebo Hyperalgesia, and Acupuncture

pp.:  128 – 140

Chapter 13 - The Relevance of Placebo and Nocebo Mechanisms for Analgesic Treatments

pp.:  140 – 150

Chapter 14 - How Placebo Responses are Formed: From Bench to Bedside

pp.:  150 – 162

Chapter 15 - Methodologic Aspects of Placebo Research

pp.:  162 – 172

Chapter 16 - Balanced Placebo Design, Active Placebos, and Other Design Features for Identifying, Minimizing and Characterizing the Placebo Response

pp.:  172 – 188

Chapter 17 - Psychological Processes that can Bias Responses to Placebo Treatment for Pain

pp.:  188 – 196

Chapter 18 - Against ‘Placebo.’ The Case for Changing our Language, and for the Meaning Response

pp.:  196 – 202

Chapter 19 - Placebo Effects in Complementary and Alternative Medicine: The Self-Healing Response

pp.:  202 – 216

Chapter 20 - Conceptualizations and Magnitudes of Placebo Analgesia Effects Across Meta-Analyses and Experimental Studies

pp.:  216 – 228

Chapter 21 - The Contribution of Desire, Expectation, and Reduced Negative Emotions to Placebo Anti-Hyperalgesia in Irritable Bowel Syndrome

pp.:  228 – 240

Chapter 22 - The Wound that Heals: Placebo, Pain and Surgery

pp.:  240 – 248

Chapter 23 - What are the Best Placebo Interventions for the Treatment of Pain?

pp.:  248 – 256

Chapter 24 - How Communication between Clinicians and Patients may Impact Pain Perception

pp.:  256 – 270

Chapter 25 - Nocebos in Daily Clinical Practice: The Potential Side Effects of the Treatment Context and the Patient–Doctor Interaction on Pain in Clinical Populations

pp.:  270 – 280

Chapter 26 - The Potential of the Analgesic Placebo Effect in Clinical Practice – Recommendations for Pain Management

pp.:  280 – 290

Chapter 27 - Placebo and Nocebo: Ethical Challenges and Solutions

pp.:  290 – 300

Index

pp.:  300 – 306

Color Plates

pp.:  306 – 322

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