Description
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.
- This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation
- The authors explain how these methods are able to provide important biological insights
Chapter
Chapter 1: Methods for Investigating the UPR in Filamentous Fungi
pp.:
50 – 80
Chapter 2: Assays for Detecting the Unfolded Protein Response
pp.:
80 – 102
Chapter 3: Analysis of the Role of Nerve Growth Factor in Promoting Cell Survival During Endoplasmic Reticulum Stress in PC12
pp.:
102 – 120
Chapter 4: Measuring ER Stress and the Unfolded Protein Response Using Mammalian Tissue Culture System
pp.:
120 – 142
Chapter 5: Real-Time Monitoring of ER Stress in Living Cells and Animals Using ESTRAP Assay
pp.:
142 – 156
Chapter 6: HIV Protease Inhibitors Induce Endoplasmic Reticulum Stress and Disrupt Barrier Integrity in Intestinal Epithelial Cells
pp.:
156 – 170
Chapter 7: Dexamethasone Induction of a Heat Stress Response
pp.:
170 – 186
Chapter 8: Detecting and Quantitating Physiological Endoplasmic Reticulum Stress
pp.:
186 – 196
Chapter 9: PI 3-Kinase Regulatory Subunits as Regulators of the Unfolded Protein Response
pp.:
196 – 208
Chapter 10: The Emerging Role of Histone Deacetylases (HDACs) in UPR Regulation
pp.:
208 – 224
Chapter 11: Immunohistochemical Detection of Activating Transcription Factor 3, a Hub of the Cellular Adaptive-Response Network
pp.:
224 – 244
Chapter 12: Experimental Approaches for Elucidation of Stress-Sensing Mechanisms of the Ire1 Family Proteins
pp.:
244 – 266
Chapter 13: Measurement and Modification of the Expression Level of the Chaperone Protein and Signaling Regulator GRP78/BiP...
pp.:
266 – 284
Chapter 14: The Endoplasmic Reticulum-Associated Degradation and Disulfide Reductase ERdj5
pp.:
284 – 308
Chapter 15: Structural Insight into the Protective Role of P58(IPK) during Unfolded Protein Response
pp.:
308 – 320
Chapter 16: Principles of IRE1 Modulation Using Chemical Tools
pp.:
320 – 344
Chapter 17: Methods to Study Stromal-Cell Derived Factor 2 in the Context of ER Stress and the Unfolded Protein Response...
pp.:
344 – 370
Chapter 18: Nitrosative Stress-Induced S-Glutathionylation of Protein Disulfide Isomerase
pp.:
370 – 382
Chapter 19: Methods for Analyzing eIF2 Kinases and Translational Control in the Unfolded Protein Response
pp.:
382 – 406
Author Index
pp.:
406 – 424
Subject Index
pp.:
424 – 441
Colour Plate
pp.:
441 – 442