The Unfolded Protein Response and Cellular Stress, Part B ( Volume 490 )

Publication series :Volume 490

Author: Conn   P. Michael  

Publisher: Elsevier Science‎

Publication year: 2011

E-ISBN: 9780123851154

P-ISBN(Paperback): 9780123851147

P-ISBN(Hardback):  9780123851147

Subject: Q2 Cytobiology;Q5 Biochemistry;Q7 Molecular Biology

Language: ENG

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Description

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.

  • This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation
  • The authors explain how these methods are able to provide important biological insights

Chapter

Front Cover

pp.:  1 – 4

Copyright

pp.:  5 – 6

Contents

pp.:  6 – 12

Contributors

pp.:  12 – 18

Preface

pp.:  18 – 20

Methods in Enzymology

pp.:  20 – 50

Chapter 1: Methods for Investigating the UPR in Filamentous Fungi

pp.:  50 – 80

Chapter 2: Assays for Detecting the Unfolded Protein Response

pp.:  80 – 102

Chapter 3: Analysis of the Role of Nerve Growth Factor in Promoting Cell Survival During Endoplasmic Reticulum Stress in PC12

pp.:  102 – 120

Chapter 4: Measuring ER Stress and the Unfolded Protein Response Using Mammalian Tissue Culture System

pp.:  120 – 142

Chapter 5: Real-Time Monitoring of ER Stress in Living Cells and Animals Using ESTRAP Assay

pp.:  142 – 156

Chapter 6: HIV Protease Inhibitors Induce Endoplasmic Reticulum Stress and Disrupt Barrier Integrity in Intestinal Epithelial Cells

pp.:  156 – 170

Chapter 7: Dexamethasone Induction of a Heat Stress Response

pp.:  170 – 186

Chapter 8: Detecting and Quantitating Physiological Endoplasmic Reticulum Stress

pp.:  186 – 196

Chapter 9: PI 3-Kinase Regulatory Subunits as Regulators of the Unfolded Protein Response

pp.:  196 – 208

Chapter 10: The Emerging Role of Histone Deacetylases (HDACs) in UPR Regulation

pp.:  208 – 224

Chapter 11: Immunohistochemical Detection of Activating Transcription Factor 3, a Hub of the Cellular Adaptive-Response Network

pp.:  224 – 244

Chapter 12: Experimental Approaches for Elucidation of Stress-Sensing Mechanisms of the Ire1 Family Proteins

pp.:  244 – 266

Chapter 13: Measurement and Modification of the Expression Level of the Chaperone Protein and Signaling Regulator GRP78/BiP...

pp.:  266 – 284

Chapter 14: The Endoplasmic Reticulum-Associated Degradation and Disulfide Reductase ERdj5

pp.:  284 – 308

Chapter 15: Structural Insight into the Protective Role of P58(IPK) during Unfolded Protein Response

pp.:  308 – 320

Chapter 16: Principles of IRE1 Modulation Using Chemical Tools

pp.:  320 – 344

Chapter 17: Methods to Study Stromal-Cell Derived Factor 2 in the Context of ER Stress and the Unfolded Protein Response...

pp.:  344 – 370

Chapter 18: Nitrosative Stress-Induced S-Glutathionylation of Protein Disulfide Isomerase

pp.:  370 – 382

Chapter 19: Methods for Analyzing eIF2 Kinases and Translational Control in the Unfolded Protein Response

pp.:  382 – 406

Author Index

pp.:  406 – 424

Subject Index

pp.:  424 – 441

Colour Plate

pp.:  441 – 442

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