Human Chorionic Gonadotropin (hCG)

Author: Cole   Laurence A.  

Publisher: Elsevier Science‎

Publication year: 2010

E-ISBN: 9780123849083

P-ISBN(Paperback): 9780123849076

P-ISBN(Hardback):  9780123849076

Subject: Q3 Genetics

Language: ENG

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Description

Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and development of fetal organs.

The book describes the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules, and examines hCG, hyperglycosylated hCG and hCG free ß-subunit, 3 separate and independent molecules with totally sovereign physiological functions.

  • It provides comprehensive information on hCG from basic science to clinical medicine

  • Written by specialists in the field

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Table of Contents

pp.:  6 – 12

Foreword

pp.:  12 – 16

About the Author

pp.:  16 – 18

Abbreviations

pp.:  18 – 22

Contributors

pp.:  22 – 24

Part A: Introduction

pp.:  24 – 58

Part B: Genetics, Synthesis, Secretion, Structure, and Degradation of hCG

pp.:  58 – 152

Part C: Biological Function of hCG

pp.:  152 – 196

Part D: Clinical Applications

pp.:  196 – 242

Part E: hCG Tests

pp.:  242 – 296

Part F: Test Applications

pp.:  296 – 372

Part G: Basic Methods

pp.:  372 – 384

Part H: Evolution, Summary, and the Future

pp.:  384 – 406

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