Biomarkers of Kidney Disease

Author: Edelstein   Charles L.  

Publisher: Elsevier Science‎

Publication year: 2010

E-ISBN: 9780123756732

P-ISBN(Paperback): 9780123756725

P-ISBN(Hardback):  9780123756725

Subject: Q1 General Biology;R473.73 Oncology Nursing;R5 Internal Medicine;R69 urological (genito - urinary diseases);R73 Oncology

Language: ENG

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Description

A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier or more effective treatments for kidney diseases.

Biomarkers of Kidney Disease reviews the basic and clinical research on biomarkers of the common kidney diseases including acute kidney injury, chronic kidney disease, renal cancer, diabetic nephropathy, glomerular disease and preeclampsia. The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. The latest techniques for biomarker detection like metabolomics and proteomics is covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation and preeclampsia.

  • Presents a comprehensive, translational source for all aspects of renal biomarkers in one reference work

Chapter

Front Cover

pp.:  1 – 4

Biomarkers in Kidney Disease

pp.:  4 – 5

Copyright

pp.:  5 – 6

Dedication

pp.:  6 – 8

Contents

pp.:  8 – 12

Contributors

pp.:  12 – 14

Foreword

pp.:  14 – 16

Preface

pp.:  16 – 18

Chapter 2 Statistical Considerations in Analysis and Interpretation of Biomarker Studies

pp.:  42 – 56

Chapter 3 The Role of Metabolomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools

pp.:  56 – 118

Chapter 4 The Role of Proteomics in the Study of Kidney Diseases andnbspin the Development of Diagnostic Tools

pp.:  118 – 194

Chapter 5 Biomarkers in Acute Kidney Injury

pp.:  194 – 250

Chapter 6 Biomarkers in Kidney Transplantation

pp.:  250 – 308

Chapter 7 Cystatin C as a Biomarker in Kidney Disease

pp.:  308 – 330

Chapter 8 Biomarkers of Renal Cancer

pp.:  330 – 368

Chapter 9 Urinary Proteomics and Candidate Biomarker Discovery for Diabetic Nephropathy

pp.:  368 – 384

Chapter 10 Biomarkers in Glomerular Disease

pp.:  384 – 402

Chapter 11 Biomarkers in Preeclampsia

pp.:  402 – 444

Index

pp.:  444 – 456

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