Handbook of Proteolytic Enzymes, Volume 1 ( 2 )

Publication series :2

Author: Barrett   Alan J.;Woessner   J. Fred;Rawlings   Neil D.  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780080984155

P-ISBN(Paperback): 9780120796113

P-ISBN(Hardback):  9780124121058

Subject: Q5 Biochemistry

Language: ENG

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Description

Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters.

This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme.

This book will prove useful to enzyme chemists and researchers.

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Table of Contents

pp.:  6 – 22

Editor biographies

pp.:  22 – 24

Contributors

pp.:  24 – 32

Preface

pp.:  32 – 34

Introduction

pp.:  34 – 38

Abbreviations

pp.:  38 – 40

PART I: ASPARTIC PEPTIDASES

pp.:  40 – 268

PART II: METALLOPEPTIDASES

pp.:  268 – 1088

Appendix 1. Organisms mentioned in the Handbook

pp.:  1088 – 1106

Appendix 2. Suppliers cited in the Handbook

pp.:  1106 – 1110

Index

pp.:  1110 – 1183

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