Guide to Techniques in Mouse Development, Part A
：Mice, Embryos, and Cells
( Volume 476 )
Publication subTitle ：Mice, Embryos, and Cells
Publication series ：Volume 476
Author： Wassarman Paul;Soriano Philippe M.
Publisher： Elsevier Science
Publication year： 2010
E-ISBN: 9780080887784
P-ISBN(Paperback): 9780123747754
P-ISBN(Hardback): 9780123747754
Subject： Q81 Bioengineering ( Biotechnology )
Language： ENG
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Description
Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development.
- Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993
- Covers new technologies and methodologies, including:
- new techniques for the cryopreservation of gametes and embryos
- production of transgenic and null (knockout) animals (use of ES cells)
- generation of conditional/inducible mutant animals
- use of gene-trap mutagenesis
- analysis of allele-specific expresion
- use of new reporter constructs
- humanizing of transgenic animals
- transcript profiling of mouse development
- imaging of mouse development
- rederivation of animals and use of mouse genomics
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