Front Cover

pp.：  1 – 4

The Chemistry of Enzyme Action

pp.：  4 – 5

Copyright Page

pp.：  5 – 8

Preface

pp.：  6 – 16

Contents

pp.：  8 – 6

Chapter 1. The energetics and specificity of enzyme – substrate interactions

pp.：  16 – 70

Chapter 2. Non-covalent forces of importance in biochemistry

pp.：  70 – 88

Chapter 3. Enzyme kinetics

pp.：  88 – 126

Chapter 4. Aspects of kinetic techniques in enzymology

pp.：  126 – 142

Chapter 5. Free-energy correlations and reaction mechanisms

pp.：  142 – 218

Chapter 6. Isotopes in the diagnosis of mechanism

pp.：  218 – 244

Chapter 7. The mechanisms of chemical catalysis used by enzymes

pp.：  244 – 286

Chapter 8. Enzyme reactions involving imine formation

pp.：  286 – 318

Chapter 9. Pyridoxal phosphate-dependent enzymic reactions: mechanism and stereochemistry

pp.：  318 – 388

Chapter 10. Transformations involving folate and biopterin cofactors

pp.：  388 – 404

Chapter 11. Glycosyl transfer – The Physicochemical Background

pp.：  404 – 448

Chapter 12. Vitamin B12

pp.：  448 – 476

Chapter 13. Reactions in micelles and similar self-organized aggregates

pp.：  476 – 520

Chapter 14. Cyclodextrins as enzyme models

pp.：  520 – 544

Chapter 15. Crown ethers as enzyme models

pp.：  544 – 578

Subject Index

pp.：  578 – 584