Natural Products Isolation
：Separation Methods for Antimicrobials, Antivirals and Enzyme Inhibitors
( Volume 43 )
Publication subTitle ：Separation Methods for Antimicrobials, Antivirals and Enzyme Inhibitors
Publication series ：Volume 43
Author： Wagman G. H.;Cooper R.
Publisher： Elsevier Science
Publication year： 1988
E-ISBN: 9780080858487
P-ISBN(Paperback): 9780444871473
P-ISBN(Hardback): 9780444871473
Subject： O62 Organic Chemistry;O65 Analytical Chemistry
Language： ENG
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Description
This new book encompasses, in great detail, the most recent progress made in the isolation and separation of natural products. It covers antibiotics, marine and plant-derived substances, enzyme inhibitors and interferons. The most recent separation methodology is described. Although there is a bias toward antibiotics, it was done because this is still the largest natural products area of research.
The fourteen chapters are written by experts in their respective fields. The first two chapters are largely devoted to new methodology applied to purification of a variety of compounds. They include an extensive review and new applications of counter-current chromatography and the newly emerging HPLC-photodiode array technology. Chapter 3 provides a review of affinity chromatography applied to the separation of antibiotics for the first time. Next are chapters on antimicrobials with an update on all the most recent &bgr;-lactam (after 1976) discoveries. A comprehensive review of a very important class of antiparasitic agents - the avermectins - follows. An update of isolation and purification of a variety of marine-derived compounds is next. The succeeding chapter is a comprehensive review of the most recent developments in isolation and purification of interferons. This is followed by a discussion of enzyme inhibitors and their isolation and purification and ties in with a chapter on plant-derived natural products, some of which are also in this same category. The final chap
Chapter