Description
The plasma membrane acts as both a boundary and a site of exchange between the outside and the inside of a cell. The cytoskeleton plays essential roles in delineating membrane protein distributions, in defining structural and functional domains in the plasma membrane, and in regulating membrane protein, and ultimately, cell function. This volume reviews the regulation of membrane protein distribution, organization, and function at the plasma membrane by the cytoskeleton. Discussions also include the roles of cytoskeleton in the structural and functional organization of membranes and membrane proteins with emphasis on key problems, the current status of understanding, experimental approaches, and future directions.
Chapter
CHAPTER 2. Once There, Making the Decision to Stay or Leave
pp.:
36 – 48
CHAPTER 3. Interactions between Microtubules and lntracellular Membranes: The Roles of Microtubule-Based Motors and Accessory Proteins
pp.:
48 – 74
CHAPTER 4. Role of the Cytoskeleton and Molecular Motors in Transport between the Golgi Complex and Plasma
Membrane
pp.:
74 – 94
CHAPTER 5. Membrane-Cytoskeleton Interaction in Regulated Exocytosis and Apical Insertion of Vesicles in Epithelial Cells
pp.:
94 – 118
CHAPTER 6. The Spectrin Cytoskeleton and Organization of Polarized Epithelial Cell Membranes
pp.:
118 – 150
CHAPTER 7. Axonal Ankyrins and Ankyrin-Binding Proteins: Potential Participants in Lateral Membrane Domains and Transcellular Connections at the Node of Ranvier
pp.:
150 – 168
CHAPTER 8. Molecular and Genetic Dissection of the Membrane Skeleton in Drosophila
pp.:
168 – 190
CHAPTER 9 .Membrane-Cytoskeleton Interactions with Cadherin Cell Adhesion Proteins: Roles of Catenins as Linker Proteins
pp.:
190 – 208
CHAPTER 10. The Desmosome: A Component System for Adhesion and Intermediate Filament Attachment
pp.:
208 – 232
CHAPTER 11. Protein Interactions in the Tight Junction: The Role of MAGUK Proteins in Regulating Tight Junction Organization and Function
pp.:
232 – 258
CHAPTER 12. Regulation of Membrane Protein Organization at the Neuromuscular Junction
pp.:
258 – 286
CHAPTER 13. lntegrin Signaling and the Platelet Cytoskeleton
pp.:
286 – 314
CHAPTER 14. Interactions between the Membrane–Cytoskeleton and CD44 during Lymphocyte Signal Transduction and Cell Adhesion
pp.:
314 – 334
CHAPTER 15. Dynamic Properties of the Lymphocyte Membrane–Cytoskeleton: Relationship to Lymphocyte Activation Status, Signal Transduction, and Protein Kinase C
pp.:
334 – 366
CHAPTER 16. Regulation of Epithelial Ion Channel Activity by the Mem brane–Cytoskeleton
pp.:
366 – 394
CHAPTER 17. Role of Actin Filament Organization in Ion Channel Activity and Cell Volume Regulation
pp.:
394 – 418
CHAPTER 18. Role of the Cytoskeleton in Membrane Alterations in Ischemic or Anoxic Renal Epithelia
pp.:
418 – 444