Linkage Thermodynamics of Macromolecular Interactions
( Volume 51 )
Publication series ：Volume 51
Author： Richards Frederic M.;Eisenberg David S.;Kim Peter S.
Publisher： Elsevier Science
Publication year： 1998
E-ISBN: 9780080582245
P-ISBN(Paperback): 9780120342518
P-ISBN(Hardback): 9780120342518
Subject： O63 Polymer Chemistry (Polymer)
Language： ENG
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Description
This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.
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