Biochemistry, Molecular Biology, and Therapeutic Implications :Nitric Oxide: Biochemistry, Molecular Biology, And Therapeutic Implications ( Volume 34 )

Publication subTitle :Nitric Oxide: Biochemistry, Molecular Biology, And Therapeutic Implications

Publication series :Volume 34

Author: August   J. Thomas;Anders   M. W.;Coyle   Joseph T.  

Publisher: Elsevier Science‎

Publication year: 1995

E-ISBN: 9780080581262

P-ISBN(Paperback): 9780120329359

P-ISBN(Hardback):  9780120329359

Subject: R74 Neurology and Psychiatry;R741 Neurology;R9 Pharmacy;R99 Toxicology (Toxicology)

Language: ENG

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Description

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. This volume contains chapters that address diverse but interrelated areas pertaining to the chemistry, biochemistry, molecular biology, and pharmacology of nitric oxide in mammalian cells. The contents form a comprehensive treatise of factors influencing the control of nitric oxide production in various cell types.

  • Presents comprehensive coverage of the chemical properties of nitric oxide and how they form the basis for the multifaceted biological actions for nitric oxide
  • Contains the most current and detailed documentation of the properties and regulation of nitric oxide synthases
  • Provides the most up-to-date review of inhalational nitric oxide therapy for treatment of respiratory dysfunction

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Contents

pp.:  6 – 20

Contributors

pp.:  20 – 26

Chapter 2. Reactions between Nitric Oxide, Superoxide, and Peroxynitrite: Footprints of Peroxynitrite in Vivo

pp.:  42 – 70

Chapter 3. Oxygen Radical–Nitric Oxide Reactions in Vascular Diseases

pp.:  70 – 96

Chapter 4. Nitric Oxide Synthases: Gene Structure and Regulation

pp.:  96 – 116

Chapter 5. Transcription of the Human Neuronal Nitric Oxide Synthase Gene in the Central Nervous System Is Mediated by Multiple Promoters'

pp.:  116 – 138

Chapter 6. Regulation of the Expression of the Inducible lsoform of Nitric Oxide Synthase

pp.:  138 – 180

Chapter 7. Regulation and Function of Inducible Nitric Oxide Synthase during Sepsis and Acute Inflammation

pp.:  180 – 196

Chapter 8. Expression and Expressional Control of Nitric Oxide Synthases in Various Cell Types

pp.:  196 – 212

Chapter 9. Control and Consequences of Endothelial Nitric Oxide Formation

pp.:  212 – 232

Chapter 10. Control of Electron Transfer in Neuronal Nitric Oxide Synthase by Calmodulin, Substrate, Substrate Analogs, and Nitric Oxide

pp.:  232 – 240

Chapter 11. Negative Modulation of Nitric Oxide Synthase by Nitric Oxide and Nitroso Compounds

pp.:  240 – 260

Chapter 12. Regulation of Nitric Oxide Synthase: Role of Oxygen Radicals and Cations in Nitric Oxide Formation

pp.:  260 – 276

Chapter 13. Why Tetrahydrobiopterin?

pp.:  276 – 288

Chapter 14. Nitric Oxide and cGMP Signaling

pp.:  288 – 302

Chapter 15. Nitric Oxide and lntracellular Heme

pp.:  302 – 318

Chapter 16. High-Level Expression of Biologically Active Soluble Guanylate Cyclase Using the Baculovirus System Is Strongly Heme-Dependent

pp.:  318 – 330

Chapter 17. cGMP Signaling through cAMP- and cGMP-Dependent Protein Kinases

pp.:  330 – 348

Chapter 18. Physiological and Toxicological Actions of Nitric Oxide in the Central Nervous System

pp.:  348 – 368

Chapter 19. S-Nitrosothiols: Chemistry, Biochemistry, and Biological Actions

pp.:  368 – 376

Chapter 20. Glyceraldehyde-3-Phosphate Dehydrogenase: A Target for Nitric Oxide Signaling

pp.:  376 – 386

Chapter 21. Nitric Oxide Donors: Biochemical Pharmacology and Therapeutics

pp.:  386 – 408

Chapter 22. Nitric Oxide Donors: A Continuing Opportunity in Drug Design

pp.:  408 – 424

Chapter 23. Nitric Oxide and Peripheral Adrenergic Neuromodulation

pp.:  424 – 440

Chapter 24. A Study on Tumor Necrosis Factor, Tumor Necrosis Factor Receptors, and Nitric Oxide in Human Fetal Glial Cultures

pp.:  440 – 464

Chapter 25. Inhaled Nitric Oxide, Clinical Rationale and Applications

pp.:  464 – 482

Chapter 26. Inhaled Nitric Oxide Therapy of Pulmonary Hypertension and Respiratory Failure in Premature and Term Neonates

pp.:  482 – 500

Chapter 27. Clinical Applications of Inhaled Nitric Oxide in Children with Pulmonary Hypertension

pp.:  500 – 530

Index

pp.:  530 – 542

Contents of Previous Volumes

pp.:  542 – 556

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