Description
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. This volume contains chapters that address diverse but interrelated areas pertaining to the chemistry, biochemistry, molecular biology, and pharmacology of nitric oxide in mammalian cells. The contents form a comprehensive treatise of factors influencing the control of nitric oxide production in various cell types.- Presents comprehensive coverage of the chemical properties of nitric oxide and how they form the basis for the multifaceted biological actions for nitric oxide
- Contains the most current and detailed documentation of the properties and regulation of nitric oxide synthases
- Provides the most up-to-date review of inhalational nitric oxide therapy for treatment of respiratory dysfunction
Chapter
Chapter 2. Reactions between Nitric Oxide, Superoxide, and Peroxynitrite: Footprints of Peroxynitrite in Vivo
pp.:
42 – 70
Chapter 3. Oxygen Radical–Nitric Oxide Reactions in Vascular Diseases
pp.:
70 – 96
Chapter 4. Nitric Oxide Synthases: Gene Structure and Regulation
pp.:
96 – 116
Chapter 5. Transcription of the Human Neuronal Nitric Oxide Synthase Gene in the Central Nervous System Is Mediated by Multiple Promoters'
pp.:
116 – 138
Chapter 6. Regulation of the Expression of the Inducible lsoform of Nitric Oxide Synthase
pp.:
138 – 180
Chapter 7. Regulation and Function of Inducible Nitric Oxide Synthase during Sepsis and Acute Inflammation
pp.:
180 – 196
Chapter 8. Expression and Expressional Control of Nitric Oxide Synthases in Various Cell Types
pp.:
196 – 212
Chapter 9. Control and Consequences of Endothelial Nitric Oxide Formation
pp.:
212 – 232
Chapter 10. Control of Electron Transfer in Neuronal Nitric Oxide Synthase by Calmodulin, Substrate, Substrate Analogs, and Nitric Oxide
pp.:
232 – 240
Chapter 11. Negative Modulation of Nitric Oxide Synthase by Nitric Oxide and Nitroso Compounds
pp.:
240 – 260
Chapter 12. Regulation of Nitric Oxide Synthase: Role of Oxygen Radicals and Cations in Nitric Oxide Formation
pp.:
260 – 276
Chapter 13. Why Tetrahydrobiopterin?
pp.:
276 – 288
Chapter 14. Nitric Oxide and cGMP Signaling
pp.:
288 – 302
Chapter 15. Nitric Oxide and lntracellular Heme
pp.:
302 – 318
Chapter 16. High-Level Expression of Biologically Active Soluble Guanylate Cyclase Using the Baculovirus System Is Strongly Heme-Dependent
pp.:
318 – 330
Chapter 17. cGMP Signaling through cAMP- and cGMP-Dependent Protein Kinases
pp.:
330 – 348
Chapter 18. Physiological and Toxicological Actions of Nitric Oxide in the Central Nervous System
pp.:
348 – 368
Chapter 19. S-Nitrosothiols: Chemistry, Biochemistry, and Biological Actions
pp.:
368 – 376
Chapter 20. Glyceraldehyde-3-Phosphate Dehydrogenase: A Target for Nitric Oxide Signaling
pp.:
376 – 386
Chapter 21. Nitric Oxide Donors: Biochemical Pharmacology and Therapeutics
pp.:
386 – 408
Chapter 22. Nitric Oxide Donors: A Continuing Opportunity in Drug Design
pp.:
408 – 424
Chapter 23. Nitric Oxide and Peripheral Adrenergic Neuromodulation
pp.:
424 – 440
Chapter 24. A Study on Tumor Necrosis Factor, Tumor Necrosis Factor Receptors, and Nitric Oxide in Human Fetal Glial Cultures
pp.:
440 – 464
Chapter 25. Inhaled Nitric Oxide, Clinical Rationale and Applications
pp.:
464 – 482
Chapter 26. Inhaled Nitric Oxide Therapy of Pulmonary Hypertension and Respiratory Failure in Premature and Term Neonates
pp.:
482 – 500
Chapter 27. Clinical Applications of Inhaled Nitric Oxide in Children with Pulmonary Hypertension
pp.:
500 – 530
Contents of Previous Volumes
pp.:
542 – 556