Transgenic Animal Technology :A Laboratory Handbook ( 2 )

Publication subTitle :A Laboratory Handbook

Publication series :2

Author: Pinkert   Carl A.  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780080574806

P-ISBN(Paperback): 9780125571661

P-ISBN(Hardback):  9780125571661

Subject: Q3 Genetics;Q95 Zoology

Language: ENG

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Description

A transgenic animal is one that is genetically modified to carry genes from another species. Transgenic species can be raised to carry potentially useful genes from a variety of species. While the topics of genetic engineering and cloning are controversial, the reality is that these technologies offer tremendous benefits to society - from offering a framework for developing and screening medical therapies, to enhancing the safety and nutrition of the food we eat.

One potential application of research into transgenic animal technology is the creation of domestic animals genetically designed to express a certain human disease and therefore serve as models for the study and treatment of human illnesses. Although many mouse models of human diseases are available today, such models in large domestic animals physiologically more similar to humans are sparse and critically needed. Further research in this field will undoubtedly uncover many more direct and indirect benefits of this technology.

Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions. This well-illustrated handbook covers the technical aspects of gene transfer — from molecular methods to whole animal considerations — for important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Table of Contents

pp.:  6 – 12

Contributors

pp.:  12 – 16

Preface

pp.:  16 – 18

PART 1: Overview

pp.:  18 – 30

PART 3: Production of Transgenic Laboratory and Domestic Animal Species

pp.:  250 – 434

PART 4: Molecular Biology, Analyses, and Enabling Technologies

pp.:  434 – 609

Appendix I: Additional Mouse Databases and Internet Resources

pp.:  609 – 613

Appendix II: Rat Databases and Internet Resources

pp.:  613 – 614

Appendix III: Swine Databases and Internet Resources

pp.:  614 – 615

Appendix V: Cattle Databases and Internet Resources

pp.:  615 – 616

Appendix IV: Sheep Databases and Internet Resources

pp.:  615 – 615

Appendix VI: Poultry Databases and Internet Resources

pp.:  616 – 616

Appendix VII: Fish Databases and Internet Resources

pp.:  616 – 618

Index

pp.:  618 – 636

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