Description
The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences.
Methods in Enzymology is now available online at ScienceDirect — full-text online of volume 1 onward.
Chapter
Chapter 1: Human Pancreatic Duct Epithelial Cell Model for KRAS Transformation
pp.：
52 – 66
Chapter 2: Mouse Model for NRAS-Induced Leukemogenesis
pp.：
66 – 76
Chapter 3: Inducible BRAF Suppression Models for Melanoma Tumorigenesis
pp.：
76 – 90
Chapter 4: A Method to Generate Genetically Defined Tumors in Pigs
pp.：
90 – 104
Chapter 5: Tools to Study the Function of the Ras-Related, Estrogen-Regulated Growth Inhibitor in Breast Cancer
pp.：
104 – 124
Chapter 6: K-Ras-Driven Pancreatic Cancer Mouse Model for Anticancer Inhibitor Analyses
pp.：
124 – 138
Chapter 7: Analysis of K-Ras Phosphorylation, Translocation, and Induction of Apoptosis
pp.：
138 – 154
Chapter 8: Regulation of RhoBTB2 by the Cul3 Ubiquitin Ligase Complex
pp.：
154 – 162
Chapter 9: Characterization of EHT 1864, a Novel Small Molecule Inhibitor of Rac Family Small GTPases
pp.：
162 – 182
Chapter 10: Analysis of Rho-GTPase Mimicry by a Family of Bacterial Type III Effector Proteins
pp.：
182 – 196
Chapter 11: Investigating the Function of Rho Family GTPases during Salmonella/Host Cell Interactions
pp.：
196 – 210
Chapter 12: Contribution of Cdc42 to Cholesterol Efflux in Fibroblasts from Tangier Disease and Werner Syndrome
pp.：
210 – 222
Chapter 13: Rac and Nuclear Translocation of Signal Transducers and Activators of Transcription Factors
pp.：
222 – 232
Chapter 14: A Method for Measuring Rho Kinase Activity in Tissues and Cells
pp.：
232 – 242
Chapter 15: Rho Kinase-Mediated Vasoconstriction in Rat Models of Pulmonary Hypertension
pp.：
242 – 256
Chapter 16: Epithelial Rho GTPases and the Transepithelial Migration of Lymphocytes
pp.：
256 – 270
Chapter 17: Invasion and Metastasis Models for Studying RhoGDI2 in Bladder Cancer
pp.：
270 – 286
Chapter 18: Characterization of the Roles of Rac1 and Rac2 GTPases in Lymphocyte Development
pp.：
286 – 306
Chapter 19: Characterization of Oligophrenin-1, a RhoGAP Lost in Patients Affected with Mental Retardation: Lentiviral Injection in Organotypic Brain Slice Cultures
pp.：
306 – 318
Chapter 20: Rho GTPases and Hypoxia in Pulmonary Vascular Endothelial Cells
pp.：
318 – 336
Chapter 21: Role of Rho GTPases in the Morphogenesis and Motility of Dendritic Spines
pp.：
336 – 354
Chapter 22: Rho GTPases in Alveolar Macrophage Phagocytosis
pp.：
354 – 366
Chapter 23: Analysis of the Elp Complex and Its Role in Regulating Exocytosis
pp.：
366 – 378
Chapter 24: Rab-Regulated Membrane Traffic between Adiposomes and Multiple Endomembrane Systems
pp.：
378 – 390
Chapter 25: Detection of Compounds That Rescue Rab1-Synuclein Toxicity
pp.：
390 – 404
Chapter 26: Analysis of Rab GTPase and GTPase-Activating Protein Function at Primary Cilia
pp.：
404 – 416
Chapter 27: Rho GTPases and Regulation of Hematopoietic Stem Cell Localization
pp.：
416 – 446
Chapter 28: In Vitro and In Vivo Assays to Analyze the Contribution of Rho Kinase in Angiogenesis
pp.：
446 – 464
Chapter 29: Analysis of Cell Migration and Its Regulation by Rho GTPases and p53 in a Three-Dimensional Environment
pp.：
464 – 476
Chapter 30: Use of Caenorhabditis elegans to Evaluate Inhibitors of Ras Function In Vivo
pp.：
476 – 502
Chapter 31: Ras-Driven Transformation of Human Nestin-Positive Pancreatic Epithelial Cells
pp.：
502 – 518
Chapter 32: The Ras Inhibitor Farnesylthiosalicylic Acid (Salirasib) Disrupts the Spatiotemporal Localization of Active Ras: A Potential Treatment for Cancer
pp.：
518 – 542
Chapter 33: Quantitative High-Throughput Cell-Based Assays for Inhibitors of ROCK Kinases
pp.：
542 – 552
Chapter 34: Tandem Affinity Purification of the BBSome, a Critical Regulator of Rab8 in Ciliogenesis
pp.：
552 – 566
Author Index
pp.：
566 – 600
Subject Index
pp.：
600 – 611
Small GTPases in Disease, Part B
( Volume 439 )
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
