Stress Hormones and Post Traumatic Stress Disorder :Basic Studies and Clinical Perspectives ( Volume 167 )

Publication subTitle :Basic Studies and Clinical Perspectives

Publication series :Volume 167

Author: Kloet   E. Ronald de;Oitzl   Melly S.;Vermetten   Eric  

Publisher: Elsevier Science‎

Publication year: 2007

E-ISBN: 9780080556475

P-ISBN(Paperback): 9780444531407

P-ISBN(Hardback):  9780444531407

Subject: Q189 Neurobiology

Language: ENG

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Description

Post-traumatic stress disorder (PTSD) arises from the experience of severe stressors and trauma. The disorder is characterized by recurrent recall of intrusive memories to the event, nightmares with insomnia, emotional numbing, hyperarousal, which are all long-lasting and relatively resistant to therapy. The focus of this book is on the question of how stress hormones are involved in PTSD. Recent evidence suggests that a dysregulation in stress hormones promotes the precipitation of PTSD and that correction of these hormones may ameliorate the disorder. This book combines state-of-the-art basic research on stress hormones from gene to behaviour with clinical research demonstrating the progress in understanding via imaging techniques, genetics, vulnerable phenotypes and co-morbidity with other disorders and physical illness.

Chapter

Cover

pp.:  1 – 6

List of contributors

pp.:  6 – 11

Preface

pp.:  11 – 14

Acknowledgements

pp.:  14 – 16

Contents

pp.:  16 – 20

Section I: The Vulnerable Phenotype: Molecules and Cells

pp.:  20 – 82

Section II: The Vulnerable Phenotype: Circuits and Behavior

pp.:  82 – 138

Section III: The Clinical Perspective: Conceptualization of PTSD and Related Disorders

pp.:  138 – 220

Section IV: The Clinical Perspective: Targets for Therapy in PTSD

pp.:  220 – 274

Section V: Short Communications

pp.:  274 – 334

Subject Index

pp.:  334 – 340

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