Disorders of Synaptic Plasticity and Schizophrenia ( Volume 59 )

Publication series ：Volume 59

Author： Smythies   John  

Publisher： Elsevier Science‎

Publication year： 2004

E-ISBN: 9780080548623

P-ISBN(Paperback): 9780123668608

P-ISBN(Hardback):  9780123668608

Subject： R749.3 Schizophrenia

Language： ENG

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Description

Schizophrenia is a severe brain disorder that affects 1% of the population. Its cause is due to the interaction of a number of abnormal genes with environmental factors. This book summarizes new advances schizophrenia research that focus on the field of neural and synaptic plasticity. Synapses in the brain in schizophrenia show a wide range of disorders, both structural and functional. This volume covers the most active and promising of these new developments, and opens up new avenues for the treatment of schizophrenia.

* Addresses new areas of research in neurotransmitters, receptors, vitamin transport, metabolism, and signaling.
* Reviews the growing field of synaptic plasticity research
* Provides links with other diseases of the Central Nervous System (CNS)

Chapter

Cover

pp.：  1 – 6

Contents

pp.：  6 – 12

Contributors

pp.：  12 – 16

Introduction

pp.：  16 – 18

Chapter 1. Loss of Spines and Neuropil

pp.：  18 – 36

Chapter 2. Schizophrenia as a Disorder of Neuroplasticity

pp.：  36 – 64

Chapter 3. The Synaptic Pathology of Schizophrenia: Is Aberrant Neurodevelopment and Plasticity to Blame?

pp.：  64 – 90

Chapter 4. Neurochemical Basis for an Epigenetic Vision of Synaptic Organization

pp.：  90 – 110

Chapter 5. Muscarinic Receptors in Schizophrenia: Is There a Role for Synaptic Plasticity?

pp.：  110 – 128

Chapter 6. Serotonin and Brain Development

pp.：  128 – 192

Chapter 7. Presynaptic Proteins and Schizophrenia

pp.：  192 – 218

Chapter 8. Mitogen-Activated Protein Kinase Signaling

pp.：  218 – 238

Chapter 9. Postsynaptic Density Scaffolding Proteins at Excitatory Synapse and Disorders of Synaptic Plasticity: Implications for Human Behavior Pathologies

pp.：  238 – 272

Chapter 10. Prostaglandin-Mediated Signaling in Schizophrenia

pp.：  272 – 290

Chapter 11. Mitochondria, Synaptic Plasticity, and Schizophrenia

pp.：  290 – 314

Chapter 12. Membrane Phospholipids and Cytokine Interaction in Schizophrenia

pp.：  314 – 344

Chapter 13. Neurotensin, Schizophrenia, and Antipsychotic Drug Action

pp.：  344 – 368

Chapter 14. Schizophrenia, Vitamin D, and Brain Development

pp.：  368 – 398

Chapter 15. Possible Contributions of Myelin and Oligodendrocyte Dysfunction to Schizophrenia

pp.：  398 – 442

Chapter 16. Brain-Derived Neurotrophic Factor and the Plasticity of the Mesolimbic Dopamine Pathway

pp.：  442 – 462

Chapter 17. S100B in Schizophrenic Psychosis

pp.：  462 – 488

Chapter 18. Oct-6 Transcription Factor

pp.：  488 – 508

Chapter 19. NMDA Receptor Function, Neuroplasticity, and the Pathophysiology of Schizophrenia

pp.：  508 – 534

Index

pp.：  534 – 548

Contents of Recent Volumes

pp.：  548 – 560

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