The Vascular Smooth Muscle Cell :Molecular and Biological Responses to the Extracellular Matrix ( Biology of Extracellular Matrix )

Publication subTitle :Molecular and Biological Responses to the Extracellular Matrix

Publication series :Biology of Extracellular Matrix

Author: Mecham   Robert P.;Schwartz   Stephen M.  

Publisher: Elsevier Science‎

Publication year: 1995

E-ISBN: 9780080543505

P-ISBN(Paperback): 9780126323108

P-ISBN(Hardback):  9780126323108

Subject: Q463 blood circulation

Language: ENG

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Description

In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also examines the proliferation and replication of SMC and its role in pharmacology and vascular disease. A must for cell, developmental, and molecular biologists, this book also will appeal to cardiologists, pathologists, and biomedical researchers interested in smooth muscle cells.

  • Presents a molecular, genetic, and developmental perspective of the vas smooth muscle cell
  • Overview sections highlight key points of chapters, including the clinical relevance of the research and expectations for future study
  • Appeals to both the basic biologist and to the biomedical researcher of vascular disease

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Contents

pp.:  6 – 12

Contributors

pp.:  12 – 14

Preface

pp.:  14 – 18

Chapter 2. Smooth Muscle Cell Differentiation during Early Development and during Intimal Thickening Formation in the Ductus Arteriosus

pp.:  34 – 54

Chapter 3. Integrins, Cytoskeletal and Extracellular Matrix Proteins in Developing Smooth Muscle Cells of Human Aorta

pp.:  54 – 98

Chapter 4. Relevance of Smooth Muscle Replication and Development to Vascular Disease

pp.:  98 – 158

Chapter 5. Smooth Muscle Gene Expression during Developmental Maturation

pp.:  158 – 180

Part 1: Molecular Identity of Smooth Muscle Cells: Overview

pp.:  180 – 284

Part 2: Smooth Muscle Cell Function from the Clinical Perspective: Overview

pp.:  284 – 418

Epilogue

pp.:  418 – 420

Index

pp.:  420 – 428

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