The Clostridia :Molecular Biology and Pathogenesis

Publication subTitle :Molecular Biology and Pathogenesis

Author: Rood   Julian I.;McClane   Bruce A.;Songer   J. Glenn  

Publisher: Elsevier Science‎

Publication year: 1997

E-ISBN: 9780080542393

P-ISBN(Paperback): 9780125950206

P-ISBN(Hardback):  9780125950206

Subject: R378.8 anaerobic bacillus Clostridium (genus)

Language: ENG

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Description

The clostridia are a group of bacteria of considerable medical and economic importance and include species responsible for generating the most potent toxins known to humans. The Clostridia: Molecular Biology and Pathogenesis is a unique work, comprising the most complete reference on the clostridia for over 20 years, bringing together the results from some of the most innovative and exciting research in the past decade. Using a principle-oriented rather than taxonomic approach, the results from molecular biology research are placed in the context of their clinical significance, and the disease process as a whole. This state-of-the-art work is truly comprehensive, covering and integrating the diverse topics of genetics, physiology, pathogenesis and cell biology. Written and edited by world-renowned authorities, material is presented to give the reader an up-to-date knowledge of the pathogenic species of this important genus. Background information is followed by details of the genetics, molecular biology, biochemistry and disease mechanisms. The structure, function and mode of action of toxins and other virulence determinants is clearly presented. As such, this work will prove essential for students, teachers, research microbiologists, infectious disease clinicians, toxin specialists, and all those working in medical or veterinary bacteriology, microbial genetics and the pharmaceutical industries.

  • Covers appropriate medical and veterinary topics
  • Co

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 8

Contents

pp.:  8 – 12

Contributors

pp.:  12 – 18

Preface

pp.:  18 – 20

Part A: GENERAL BIOLOGY

pp.:  20 – 52

Part B: GENOME ORGANIZATION AND MOLECULAR GENETICS

pp.:  52 – 112

Part C: CLOSTRIDIA IN CLINICAL PRACTICE

pp.:  112 – 202

Part D: PATHOGENESIS OF INFECTIONS

pp.:  202 – 228

Part E: MEMBRANE ACTIVE TOXINS AND ENZYMES

pp.:  228 – 278

Part F: NEUROTOXINS

pp.:  278 – 342

Part G: ENTEROTOXINS

pp.:  342 – 428

Part H: OTHER TOXINS AND EXTRACELLULAR ENZYMES

pp.:  428 – 468

Part I: REGULATION OF VIRULENCE

pp.:  468 – 508

Part J: CONTROL AND DIAGNOSIS

pp.:  508 – 544

Index

pp.:  544 – 554

Color Plate Section

pp.:  554 – 556

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