Protein Adaptations and Signal Transduction ( Volume 2 )

Publication series :Volume 2

Author: Storey   K. B.;Storey   J. M.  

Publisher: Elsevier Science‎

Publication year: 2001

E-ISBN: 9780080539966

P-ISBN(Paperback): 9780444507594

P-ISBN(Hardback):  9780444507594

Subject: Q51 Protein

Language: ENG

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Description

This volume of Cell and Molecular Responses to Stress has two broad themes: an examination of selected protein adaptations that support stress tolerance and an analysis of signal transduction systems, those critical links between the perception of stress and the activation of the coordinated metabolic responses that ensure survival. Several chapters deal with adaptive responses to environmental cold temperature and highlight novel advances in mammalian hibernation, low temperature enzyme function, cold-shock and antifreeze proteins, and freezing survival. Other chapters stretch out to explore biochemical responses to diverse stresses including water stress, mechanical stress, nutrient availability, oxygen limitation and oxidative stress. The integral roles of protein kinases, transcription factors, oxygen free radicals, and oxygen-sensitive ion channels in the detection and mediation of stress responses are explored. The multiplicity of responses is emphasized and shows us the vast potential of cells and organisms to respond to innumerable stresses, great and small, and the regulatory principles and mechanisms that are used to allow life to adapt and endure in every environment on Earth.


Featuring:


  • A discussion of new advances in understanding protein adaptations that support organismal survival of stress.

  • State-of-the-art analysis of key components of cellular signal transduction pathways including protein kinases and cal

Chapter

Cover

pp.:  1 – 12

Preface

pp.:  6 – 8

List of Contributors

pp.:  8 – 20

Contents

pp.:  12 – 6

Chapter 1. Signal Transduction and Gene Expression in the Regulation of Natural Freezing Survival

pp.:  20 – 40

Chapter 2. Drosophila as a Model Organism for the Transgenic Expression of Antifreeze Proteins

pp.:  40 – 50

Chapter 3. Cold-adapted Enzymes: An Unachieved Symphony

pp.:  50 – 62

Chapter 4. The Role of Cold-shock Proteins in Low-temperature Adaptation

pp.:  62 – 76

Chapter 5. Hibernation: Protein Adaptations

pp.:  76 – 92

Chapter 6. Aquaporins and water stress

pp.:  92 – 106

Chapter 7. Gene Expression Associated with Muscle Adaptation in Response to Physical Signals-

pp.:  106 – 116

Chapter 8. Early Responses to Mechanical Stress: From Signals at the Cell Surface to Altered Gene Expression

pp.:  116 – 130

Chapter 9. Fasting and Refeeding: Models of Changes in Metabolic Efficiency

pp.:  130 – 148

Chapter 10. Nutritional Regulation of Hepatic Gene Expression

pp.:  148 – 164

Chapter 11. The AMP-activated/SNF1 Protein Kinases: Key Players in the Response of Eukaryotic Cells to Metabolic Stress-

pp.:  164 – 182

Chapter 12. Cellular Regulation of Protein Kinase C

pp.:  182 – 194

Chapter 13. Mitogen-activated protein kinases and stress

pp.:  194 – 214

Chapter 14. How to Activate Intrinsic Stress Resistance Mechanisms to Obtain Therapeutic Benefit

pp.:  214 – 222

Chapter 15. Regulation of Ion Channel Function and Expression by Hypoxia

pp.:  222 – 232

Chapter 16. Ca2+ Dynamics Under Oxidant Stress in the Cardiovascular System

pp.:  232 – 248

Chapter 17. Role of NF-E2 Related Factors in Oxidative Stress

pp.:  248 – 258

Chapter 18. Signal Transduction Cascades Responsive to Oxidative Stress in the Vasculature-

pp.:  258 – 272

Chapter 19. Oxidative Stress Signaling

pp.:  272 – 282

Chapter 20. Antioxidant Defenses and Animal Adaptation to Oxygen Availability During Environmental Stress

pp.:  282 – 308

Index

pp.:  308 – 312

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