Peptide Receptors, Part I ( Volume 16 )

Publication series :Volume 16

Author: Bjorklund   A.;Hokfelt   T.;Quinton   P.  

Publisher: Elsevier Science‎

Publication year: 2000

E-ISBN: 9780080538587

P-ISBN(Paperback): 9780444829726

P-ISBN(Hardback):  9780444829726

Subject: R322.8 neuroradiology

Language: ENG

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Description

During the last few years, the pace of research in the field of neuropeptide receptors has increased steadily: new neuropeptides were discovered, and the classification of receptor subtypes has been refined. It thus appeared essential to update the information. Peptide Receptors Part I summarizes current knowledge on ten distinct peptide families.
This volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry, and immunocytochemistry images. Application of these classical techniques and of new approaches such as transgenic and knock-out animals has revealed a distinct species and tissue specific variation in receptor subtypes expression and pharmacology in the mammalian central nervous system.
The functional role of neuropeptides and their receptors in the CNS has been investigated thanks to the development of potent and selective receptor antagonists and agonists. The development of specific neuropeptide-related molecules will help to get a better understanding of receptor subtype physiology and neuronal distribution and may lead to innovative treatments in a variety of brain disorders.

Chapter

Cover

pp.:  1 – 10

List of Contributors

pp.:  4 – 8

Preface

pp.:  8 – 20

TOC$Contents

pp.:  10 – 4

CH$Chapter II. Brain PACAP/VIP receptors: regional distribution, functional properties and physiological relevance

pp.:  64 – 98

CH$Chapter III. Localization of angiotensin receptors in the nervous system

pp.:  98 – 144

CH$Chapter IV. Brain endothelin and natriuretic peptide receptors

pp.:  144 – 182

CH$Chapter V. Neuropeptide FF receptors

pp.:  182 – 214

CH$Chapter VI. Neurokinin receptors in the CNS

pp.:  214 – 260

CH$Chapter VII. Brain kallikrein–kinin system: from receptors to neuronal pathways and physiological functions

pp.:  260 – 320

CH$Chapter VIII. Calcitonin gene-related peptide (CGRP), amylin and adrenomedullin: anatomical localization and biological functions in the mammalian and human brains

pp.:  320 – 394

CH$Chapter IX. Neuropeptide Y, peptide YY and pancreatic polypeptide receptor proteins and mRNAs in mammalian brains

pp.:  394 – 496

CH$Chapter X . Multiple brain corticotropin-releasing factor receptors and binding protein

pp.:  496 – 528

IDX$Subject Index

pp.:  528 – 538

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