Novel Anticancer Agents :Strategies for Discovery and Clinical Testing

Publication subTitle :Strategies for Discovery and Clinical Testing

Author: Adjei   Alex A.;Buolamwini   John K.  

Publisher: Elsevier Science‎

Publication year: 2011

E-ISBN: 9780080537757

P-ISBN(Paperback): 9780120885619

P-ISBN(Hardback):  9780120885619

Subject: R9 Pharmacy

Language: ENG

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Description

Novel Anticancer Agents offers pertinent basic science information on strategies used for the rational design and discovery of novel anticancer agents, and, in addition, translational studies involving clinical trial design and execution with these novel, mostly cytostatic agents. This book covers basic science strategies that are being used in drug discovery and preclinical evaluation focused on novel molecular targets, as well as clinical trial methodology including clinical pharmacokinetics and imaging to address issues of efficacy evaluation of the new, relatively non-cytotoxic anticancer agents.

At present, there is no book that provides such an integration of basic and clinical studies of novel anticancer agents, covering both drug discovery and translational research extensively.

  • Addresses the critical issues involved in the development of novel agents for cancer therapy by experts in the field
  • Presents drug discovery strategies
  • Discusses regulatory issues surrounding drug development

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Contents

pp.:  6 – 12

Contributors

pp.:  12 – 16

Preface

pp.:  16 – 18

Part II: Methods for Clinical Testing of Novel Agents

pp.:  268 – 448

Index

pp.:  448 – 459

Color Plate Section

pp.:  459 – 479

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