Immunopharmacology of Free Radical Species ( Handbook of Immunopharmacology )

Publication series :Handbook of Immunopharmacology

Author: Page   Clive;Blake   David;Winyard   Paul G.  

Publisher: Elsevier Science‎

Publication year: 1995

E-ISBN: 9780080534541

P-ISBN(Paperback): 9780121035204

P-ISBN(Hardback):  9780121035204

Subject: R967 Immunopharmacology

Language: ENG

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Description

Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Contents

pp.:  6 – 12

Contributors

pp.:  12 – 16

Series Preface

pp.:  16 – 18

Preface

pp.:  18 – 20

Chapter 1. Methods for the Detection and Measurement of Reactive Radical Species in vivo and in vitro

pp.:  20 – 42

Chapter 2. Lipid Peroxidation and Cardiovascular Disease

pp.:  42 – 58

Chapter 3. Free Radicals and Antioxidants in Atherosclerosis

pp.:  58 – 72

Chapter 4. Oxidant Stress and the Heart: Modulation of Ion Transport Mechanisms during Ischaemia and Reperfusion

pp.:  72 – 92

Chapter 5. Free Radicals in Central Nervous System Diseases

pp.:  92 – 104

Chapter 6. Renal Transplantation and Ischaemia–Reperfusion Injury

pp.:  104 – 116

Chapter 7. A Vascular Basis for Free Radical Involvement in Inflammatory Joint Disease

pp.:  116 – 132

Chapter 8. Reactive Oxygen Species in Skin Inflammation

pp.:  132 – 146

Chapter 9. Free Radicals, Inflammation and Eye Diseases

pp.:  146 – 162

Chapter 10. Free Radicals in Gastrointestinal and Hepatic Disease

pp.:  162 – 194

Chapter 11. Free Radicals, Muscle Fatique and Damage

pp.:  194 – 202

Chapter 12. Free Radicals, Oxidative Stress and Diabetes Mellitus

pp.:  202 – 218

Chapter 13. DNA Damage by Free Radicals: Carcinogenic Implications

pp.:  218 – 234

Chapter 14. Free Radicals in Lung Inflammation and Environmental Exposure to Pollutants

pp.:  234 – 252

Chapter 15. Free Radicals and Liver Injury

pp.:  252 – 266

Chapter 16. The Conioses: Organotypic Inflammatory Oxidative Responses to Environmental Particulate Pollutants

pp.:  266 – 282

Chapter 17. Reactive Oxygen: Recent Therapeutic Intervention Strategies

pp.:  282 – 298

Glossary

pp.:  298 – 308

Key to Illustrations

pp.:  308 – 314

Index

pp.:  314 – 322

Color Plate Section

pp.:  322 – 324

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