Caloric Restriction: A Key to Understanding and Modulating Aging :A Key to Understanding and Modulating Aging ( Volume 1 )

Publication subTitle :A Key to Understanding and Modulating Aging

Publication series :Volume 1

Author: Masoro   E. J.  

Publisher: Elsevier Science‎

Publication year: 2002

E-ISBN: 9780080528427

P-ISBN(Paperback): 9780444511621

P-ISBN(Hardback):  9780444511621

Subject: R3 Basic Medical;R592 geriatrics;TS2 food industry

Language: ENG

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Description

For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous at advanced ages.

What is the reason for this change in the usual pattern of aging? The evidence is overwhelming that the life extension results from a slowing of aging processes. And the factor responsible is the decrease in caloric intake. The obvious question: How does this factor work? A good question - and the reason that research on the anti-aging action of caloric restriction is today one of the most studied research areas in biological gerontology. For it is felt that if the biological mechanisms of the anti-aging action of caloric restriction can be uncovered, we would gain an understanding of the basic nature of aging processes, which would, in turn, yield possible interventions in human aging. This book aims to provide the growing number of researchers in this field (faculty, postdoctoral trainees, and graduate students) with a detailed knowledge of what is known about caloric restriction within the frame of gerontology, as well as insights on future of this field.

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Table of Contenst

pp.:  6 – 8

Preface

pp.:  8 – 10

Chapter 1. Overview

pp.:  10 – 20

Chapter 2. Mortality Characteristics

pp.:  20 – 30

Chapter 3. Molecular and Cellular Biology

pp.:  30 – 60

Chapter 4. Organismic Physiology

pp.:  60 – 102

Chapter 5. Age-Associated Diseases

pp.:  102 – 124

Chapter 6. Mechanisms of the Anti-Aging Action of Caloric Restriction

pp.:  124 – 166

Chapter 7. Evolution of Anti-Aging Action of Caloric Restriction

pp.:  166 – 174

Chapter 8. Caloric Restriction Mimetics

pp.:  174 – 188

Index

pp.:  188 – 194

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