Amyloid, Prions, and Other Protein Aggregates, Part B ( Volume 412 )

Publication series :Volume 412

Author: Wetzel   Ronald;Kheterpal   Indu  

Publisher: Elsevier Science‎

Publication year: 2006

E-ISBN: 9780080522548

P-ISBN(Paperback): 9780121828172

P-ISBN(Hardback):  9780121828172

Subject: Q2 Cytobiology;Q5 Biochemistry

Language: ENG

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Description

The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part C (volume 413) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies.

  • Presents detailed protocols
  • Includes troubleshooting tips
  • Provides coverage on structural biology, computational methods, and biology

Chapter

Cover

pp.:  1 – 4

Title Page

pp.:  4 – 5

Copyright Page

pp.:  5 – 6

Table of Contents

pp.:  6 – 10

Contributors to Volume 412

pp.:  10 – 14

Preface

pp.:  14 – 18

Volumes in Series

pp.:  18 – 42

Section I: Characterization of Protein Deposition In Vivo and Ex Vivo

pp.:  42 – 224

Section II: Cell and Animal Models of Amyloid Formation and Toxicity

pp.:  224 – 324

Section III: Computational Approaches and Theory

pp.:  324 – 408

Author Index

pp.:  408 – 436

Subject Index

pp.:  436 – 446

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