Progress in Medicinal Chemistry ( Volume 40 )

Publication series ：Volume 40

Author： King   F. D.;Oxford   A. W.  

Publisher： Elsevier Science‎

Publication year： 2002

E-ISBN: 9780080515205

P-ISBN(Paperback): 9780444510549

P-ISBN(Hardback):  9780444510549

Subject： R313 Medical Chemistry

Language： ENG

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Description

This volume features accounts of the biological rationale, design and clinical potential of drug molecules; summaries of structure-activity relationships in topical areas of medicinal chemistry and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.

Chapter

Front Cover

pp.：  1 – 4

Progress in Medicinal Chemistry, Volume 40

pp.：  4 – 5

Copyright Page

pp.：  5 – 6

Contents

pp.：  6 – 8

Preface

pp.：  8 – 10

List of Contributors

pp.：  10 – 12

Chapter 1. The Discovery and Development of Atorvastatin, a Potent Novel Hypolipidemic Agent

pp.：  12 – 34

Chapter 2. Discovery of CEP-1347/KT-7515, an Inhibitor of the JNK/SAPK Pathway for the Treatment

pp.：  34 – 74

Chapter 3. Discovery of Second Generation Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors of HIV-1

pp.：  74 – 118

Chapter 4. Molecular Modeling of Opioid Receptor-Ligand Complexes

pp.：  118 – 148

Subject Index

pp.：  148 – 150

Author Index (Vols. 1–40)

pp.：  150 – 156

Subject Index (Vols. 1–40)

pp.：  156 – 162

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