Protein Modules and Protein-Protein Interactions ( Volume 61 )

Publication series :Volume 61

Author: Janin   Joël  

Publisher: Elsevier Science‎

Publication year: 2002

E-ISBN: 9780080493756

P-ISBN(Paperback): 9780120342617

P-ISBN(Hardback):  9780120342617

Subject: Q5 Biochemistry;Q6 Biophysics;Q7 Molecular Biology

Language: ENG

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Description

Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction.

  • Comprehensive overview of different facets of macromolecule interactions
  • Computational and bioinformatics aspects of analyzing protein modules and their interactions
  • Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Contents

pp.:  6 – 10

Chapter 1.Introduction

pp.:  10 – 18

Chapter 2. Structural Basis of Macromolecular Recognition

pp.:  18 – 84

Chapter 3. Sequences Analysis of Multidomain Proteins: Past Perspectives and Future Directions

pp.:  84 – 108

Chapter 4. Identification of Transiently Interacting Proteins and of Stable Protein Complexes

pp.:  108 – 128

Chapter 5. Molecular Recognition in Antibody–Antigen Complexes

pp.:  128 – 170

Chapter 6. Molecular Recognition by SH2 Domains

pp.:  170 – 220

Chapter 7. How SH3 Domain Recognize Proline

pp.:  220 – 278

Chapter 8. Structural Biology of elF4F: mRNA Recognition and Preparation in Eukaryotic Translation Initiation

pp.:  278 – 308

AUTHOR INDEX

pp.:  308 – 336

SUBJECT INDEX

pp.:  336 – 344

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