Drug Discovery and Design ( Volume 56 )

Publication series :Volume 56

Author: Richards   Frederic M.;Eisenberg   David S.;Kim   Peter S.  

Publisher: Elsevier Science‎

Publication year: 2001

E-ISBN: 9780080493381

P-ISBN(Paperback): 9780120342563

P-ISBN(Hardback):  9780120342563

Subject: Q51 Protein

Language: ENG

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Description

Strategies to reduce medical uncertainty and build evidence have become critical to the advancement of medical knowledge and modern medical practice. As new techniques and strategies have arisen, so has the need for a current reference work. Drug Discovery and Design examines the latest research in the development of these new strategies. Some of the topics covered include angiotensin converting enzyme inhibitors, HIV protease inhibitors, PPAR agonists for diabetes, and glucan synthase antifungal agents.

Chapter

Front Cover

pp.:  1 – 4

Drug Discovery and Design

pp.:  4 – 5

Copyright Page

pp.:  5 – 6

CONTENTS

pp.:  6 – 12

PREFACE

pp.:  12 – 14

Chapter 3. HMG-CoA Reductase Inhibitors

pp.:  90 – 128

Chapter 4. Cyclooxygenase-2 Inhibitors

pp.:  128 – 156

Chapter 5. 5α-Reductase Inhibitors

pp.:  156 – 194

Chapter 6. Peroxisome Proliferator-Activated Receptor (PPAR)γ Agonists for Diabetes

pp.:  194 – 226

Chapter 7. Discovery and Clinical Development of HIV-1 Protease Inhibitors

pp.:  226 – 266

Chapter 8. Calcineurin Inhibitors and the Generalization of the Presenting Protein Strategy

pp.:  266 – 306

Chapter 9. Pure Selective Estrogen Receptor Modulators, New Molecules Having Absolute Cell Specificity Ranging from Pure Antiestrogenic to Complete Estrogen-Like Activities

pp.:  306 – 382

Chapter 10. Monoclonal Antibody Therapy

pp.:  382 – 436

Chapter 11. Glucan Synthase Inhibitors as Antifungal Agents

pp.:  436 – 490

AUTHOR INDEX

pp.:  490 – 566

SUBJECT INDEX

pp.:  566 – 582

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