Description
Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.
Chapter
Chapter 2. Immunoglobulin Heavy Chain Genes of Mouse
pp.：
34 – 42
Chapter 3. Immunoglobulin K Genes of Human and Mouse
pp.：
42 – 52
Chapter 4. Immunoglobulin Lambda (IGL) Genes of Human and Mouse
pp.：
52 – 76
Chapter 5. The Mechanism of V(D)J Recombination
pp.：
76 – 98
Chapter 6. Transcription of Immunoglobulin Genes
pp.：
98 – 116
Chapter 7. Early B Cell Development to a Mature, Antigen-Sensitive Cell FRITZ MELCHERS AND PAUL KINCADE
pp.：
116 – 142
Chapter 8. Allelic Exclusion, Isotypic Exclusion, and the Developmental Regulation of V(D)J Recombination
pp.：
142 – 156
Chapter 9. The Development of Human B Lymphocytes
pp.：
156 – 170
Chapter 10. Development and Function of B Cell Subsets
pp.：
170 – 176
Chapter 11. Structure and Function of B Cell Antigen Receptor Complexes
pp.：
176 – 186
Chapter 12. Regulation of Antigen Receptor Signaling by the Co-Receptors, CD19 and CD22
pp.：
186 – 202
Chapter 13. The Dynamic Structure of Antibody Responses
pp.：
202 – 218
Chapter 14. Dynamics of B Cell Migration to and within Secondary Lymphoid Organs
pp.：
218 – 238
Chapter 15. Characteristics of Mucosal B Cells with Emphasis on the Human Secretory Immune System
pp.：
238 – 262
Chapter 16. The Cellular Basis of B Cell Memory
pp.：
262 – 276
Chapter 17. Immunoglobulin Assembly and Secretion
pp.：
276 – 290
Chapter 18. Fc and Complement Receptors
pp.：
290 – 304
Chapter 19. Regulation of Class Switch Recombination
pp.：
304 – 322
Chapter 20. Molecular Mechanism of Class Switch Recombination
pp.：
322 – 342
Chapter 21. Molecular Mechanism of Hypermutation
pp.：
342 – 354
Chapter 22. Selection During Antigen-Driven B Cell Immune Responses: The Basis for High Affinity Antibody
pp.：
354 – 364
Chapter 23. Chromosomal Translocations in B-Cell Leukemias and Lymphomas
pp.：
364 – 380
Chapter 24. Classification and Characteristics of Mouse B Cell—Lineage Lymphomas
pp.：
380 – 396
Chapter 25. B Cells Producing Pathogenic Autoantibodies
pp.：
396 – 418
Chapter 26. Immunodeficiencies Caused by B-Cell Defects
pp.：
418 – 432
Chapter 27. Diverse Forms of Immunoglobulin Genes in Lower Vertebrates
pp.：
432 – 448
Chapter 28. Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Vertebrates: A Key Role for GALT
pp.：
448 – 464
Chapter 29. The Zebrafish Immune System
pp.：
464 – 488
Chapter 30. The Origin of V(D)J Diversification
pp.：
488 – 506
Chapter 31. Antibody Structure and Recognition of Antigen
pp.：
506 – 526
Chapter 32. Monoclonal Antibodies from Display Libraries
pp.：
526 – 548
Chapter 33. Humanization of Monoclonal Antibodies
pp.：
548 – 562
Chapter 34. Human Monoclonal Antibodies from Translocus Mice
pp.：
562 – 578
Color Plate Section
pp.：
606 – 630
Molecular Biology of B Cells
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