Principles and Methods of Immunotoxicology

Author： Descotes   Jacques  

Publisher： Elsevier Science‎

Publication year： 2004

E-ISBN: 9780080472997

P-ISBN(Paperback): 9780444510938

P-ISBN(Hardback):  9780444510938

Subject： R99 Toxicology (Toxicology)

Language： ENG

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Description

This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.

Chapter

Cover

pp.：  1 – 7

Preface

pp.：  7 – 9

Contents

pp.：  9 – 17

Chapter 1 Definition, history, and scope of immunotoxicology

pp.：  17 – 35

Chapter 2 The immune system: a toxicologist’s overview

pp.：  35 – 71

Chapter 3 Health consequences of immunotoxic effects

pp.：  71 – 143

Chapter 4 Mechanisms of immunotoxic effects

pp.：  143 – 179

Chapter 5 Nonclinical evaluation of unexpected immunosuppression

pp.：  179 – 221

Chapter 6 Nonclinical evaluation of unexpected immunostimulation

pp.：  221 – 235

Chapter 7 Nonclinical evaluation of the potential for hypersensitivity

pp.：  235 – 259

Chapter 8 Nonclinical evaluation of the potential for autoimmunity

pp.：  259 – 273

Chapter 9 Regulatory aspects of immunotoxicity evaluation

pp.：  273 – 285

Chapter 10 Nonclinical strategies of immunotoxicity evaluation and risk assessment

pp.：  285 – 311

Chapter 11 Clinical immunotoxicology

pp.：  311 – 327

Chapter 12 Immunotherapy of human poisonings

pp.：  327 – 343

Chapter 13 Chemical immunoteratology and developmental immunotoxicology

pp.：  343 – 371

Chapter 14 Immunotoxicity and wildlife

pp.：  371 – 379

Chapter 15 New methods in immunotoxicology

pp.：  379 – 395

Chapter 16 Classification of immunotoxicants

pp.：  395 – 403

LIST OF ABBREVIATIONS

pp.：  403 – 405

Index

pp.：  405 – 415

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