Synthesis of Essential Drugs

Author: Vardanyan   Ruben;Hruby   Victor  

Publisher: Elsevier Science‎

Publication year: 2006

E-ISBN: 9780080462127

P-ISBN(Paperback): 9780444521668

P-ISBN(Hardback):  9780444521668

Subject: R9 Pharmacy

Language: ENG

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Description

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs.

This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.

Synthesis of Essential Drugs<

Chapter

front cover

pp.:  1 – 5

copyright

pp.:  5 – 8

Preface

pp.:  8 – 10

front matter

pp.:  8 – 8

table of contents

pp.:  10 – 18

body

pp.:  18 – 18

General Anesthetics

pp.:  18 – 26

Local Anesthetics

pp.:  26 – 36

Analgesics

pp.:  36 – 74

Soporific Agents (Hypnotics and Sedative Drugs)

pp.:  74 – 86

Anxiolytics (Tranquilizers)

pp.:  86 – 100

Antipsychotics (Neuroleptics)

pp.:  100 – 120

Antidepressants

pp.:  120 – 134

Central Nervous System Stimulants

pp.:  134 – 142

Antiepileptic Drugs

pp.:  142 – 152

Antiparkinsonian Drugs

pp.:  152 – 160

Adrenergic (Sympathomimetic) Drugs

pp.:  160 – 178

Adrenoblocking Drugs

pp.:  178 – 196

Cholinomimetics

pp.:  196 – 212

Anticholinergic Drugs

pp.:  212 – 226

Muscle Relaxants

pp.:  226 – 236

Antihistamine Drugs

pp.:  236 – 254

Cardiotonic Drugs

pp.:  254 – 262

Antiarrhythmic Drugs

pp.:  262 – 274

Antianginal Drugs

pp.:  274 – 286

Hypolipidemic Agents

pp.:  286 – 294

Diuretics

pp.:  294 – 312

Antihypertensive Drugs

pp.:  312 – 328

Drugs for Treating Respiratory System Illnesses

pp.:  328 – 340

Anticoagulants, Antiaggregants, Thrombolytics, and Hemostatics

pp.:  340 – 354

Thyroid Hormone and Antithyroid Drugs

pp.:  354 – 360

Insulin and Synthetic Hypoglycemic Agents

pp.:  360 – 366

Corticosteroids

pp.:  366 – 382

Female Sex Hormones

pp.:  382 – 398

Male Sex Hormones and Anabolic Steroids

pp.:  398 – 406

Antineoplastics

pp.:  406 – 436

Immunopharmacological Drugs

pp.:  436 – 442

Antibiotics

pp.:  442 – 516

Antimicrobial Drugs

pp.:  516 – 542

Antimycobacterial Drugs

pp.:  542 – 552

Antifungal Drugs

pp.:  552 – 566

Antiviral Drugs

pp.:  566 – 576

Drugs for Treating Protozoan Infections

pp.:  576 – 600

Antihelmintic Drugs

pp.:  600 – 612

Index

pp.:  612 – 636

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