APC gene: database of germline and somatic mutations in human tumors and cell lines

Author: Laurent‐Puig Pierre   Béroud Christophe   Soussi Thierry  

Publisher: Oxford University Press

ISSN: 1362-4962

Source: Nucleic Acids Research, Vol.26, Iss.1, 1998-01, pp. : 271-273

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Abstract

A database (http://perso.curie.fr/tsoussi ) is described, in which over 1000 mutations in the human APC gene of tumors (colon cancer predominantly) are compiled from the literature. It includes both molecular information about the mutations and clinical data about the patients. Software has been designed to analyse all this information in the database.