Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study

Author: Chillemi Giovanni   Fiorani Paola   Castelli Silvia   Bruselles Alessandro   Benedetti Piero   Desideri Alessandro  

Publisher: Oxford University Press

ISSN: 1362-4962

Source: Nucleic Acids Research, Vol.33, Iss.10, 2005-01, pp. : 3339-3350

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Abstract