Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I

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Oxford University Press

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Mutations Within a Conserved Region of Vaccinia Topoisomerase Affect the DNA Cleavage-Religation Equilibrium

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Characterization of the DNA-binding domain and identification of the active site residue in the ‘Gyr A’ half of Leishmania donovani topoisomerase II

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The C‐terminal domain but not the tyrosine 723 of human DNA topoisomerase I active site contributes to kinase activity

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An insight into the active site of a type I DNA topoisomerase from the kinetoplastid protozoan Leishmania donovani

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