Thermodynamic stability and Watson–Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect

Author： Ui-Tei Kumiko   Naito Yuki   Nishi Kenji   Juni Aya   Saigo Kaoru  

Publisher： Oxford University Press

ISSN： 1362-4962

Source： Nucleic Acids Research, Vol.36, Iss.22, 2008-12, pp. : 7100-7109

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