ESHRE PGD Consortium data collection V: Cycles from January to December 2002 with pregnancy follow-up to October 2003

Author： Harper J.C. Boelaert K. Geraedts J. Harton G. Kearns W.G. Moutou C. Muntjewerff N. Repping S. SenGupta S. Scriven P.N. Traeger-Synodinos J. Vesela K. Wilton L. Sermon K.D.

Publisher： Oxford University Press

ISSN： 1460-2350

Source： Human Reproduction, Vol.21, Iss.1, 2006-01, pp. : 3-21

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Abstract

The fifth report of the ESHRE PGD Consortium is presented (data collection V). For the first time, the cycle data were collected for one calendar year (2002) in the following October, so that data collection was complete for pregnancies and babies. The data were collected using a Filemaker Pro database and divided into referrals, cycles, pregnancies and babies. There are currently 66 active centres registered with the consortium; however, the data presented here were obtained from 43 centres and included 1603 referrals, 2219 cycles, 485 pregnancies and 382 babies born. The cycle data were divided into preimplantation genetic diagnosis (PGD) for inherited disorders (including chromosome abnormalities, sexing for X-linked disease and monogenic disorders), aneuploidy screening (PGS) and the use of PGD for social sexing. Data collection V is compared with the previous cumulative data collection (I–IV), which comprised 4058 PGD/PGS cycles that reached oocyte retrieval.