Author： Zhang Gen-Hua Zhang Hai-Yun Deng Shao-Ping Qin Yu-Mei
Publisher： Oxford University Press
ISSN： 1464-3553
Source： Chemical Senses, Vol.33, Iss.4, 2008-04, pp. : 357-362
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Abstract
The regional differences between distribution patterns and -gustducin expression patterns of the fungiform (FF) taste buds were investigated in the adult mouse, using hematoxylin-eosin staining and immunofluorescence histochemistry on the most anterior region of the tongue (the first millimeter) through the intermediate region of the tongue (the last 14 mm). Paraffin sections were prepared from the tip to posterior regions (anterior and intermediate region containing the FF taste buds) of the adult mouse tongue. Results indicate that there were significant regional differences in size and density of taste buds, the cell counts of the single taste bud, and the -gustducinimmunoreactive taste buds between the 2 regions. The taste bud had a characteristic onion-like appearance, and the -gustducinimmunoreactive cell was spindle shaped with elongated processes extending from the base to the pore of the taste buds. These results provide a detailed insight to better understand regional descriptions of mouse taste bud density and size and -gustducin expression with the mouse model.
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