Knockdown of prion protein (PrP) by RNA interference weakens the protective activity of wild-type PrP against copper ion and antagonizes the cytotoxicity of fCJD-associated PrP mutants in cultured cells

Author: Wang Zhao-Yun   Tian Chan   Jing Yuan-Yuan   Gong Han-Shi   Guo Yan   Shi Qi   Chen Cao   Zhu Shu-Ying   Dong Xiao-Ping  

Publisher: Spandidos Publications

ISSN: 1107-3756

Source: International Journal of Molecular Medicine, Vol.28, Iss.3, 2011-09, pp. : 413-421

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Abstract