Electron Paramagnetic Resonance Spectrum of Human Serum Copper

Author: Kakuda T.   Tanaka H.   Kimoto E.   Morishige F.  

Publisher: Society for Applied Spectroscopy

ISSN: 0003-7028

Source: Applied Spectroscopy, Vol.34, Iss.3, 1980-05, pp. : 276-280

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Abstract

The electron paramagnetic resonance signal of the cupric ion (its perpendicular component) at −196°C was found to be different in shape in human blood plasma and serum. On the addition of acid, substrate of ceruloplasmin, reducing agent, or denaturing agent, serum exhibited a complex electron paramagnetic resonance spectrum similar to that of a copper-diethyldithiocarbamate complex in an organic solvent, with a simultaneous disappearance of the cupric ion signal. Such an electron paramagnetic resonance spectrum occurred only from human serum but not from animal (guinea pig, mouse, rat, cattle, or monkey) serum.