High-Throughput Screening of Enzyme Inhibitors: Simultaneous Determination of Tight-Binding Inhibition Constants and Enzyme Concentration

By Kuzmič P.   Elrod K.C.   Cregar L.M.   Sideris S.   Rai R.   Janc J.W.  

Analytical Biochemistry, Vol. 286, Iss. 1, 2000-11 ,pp. : 45-50

Elsevier

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Accurate Determination of Rate Constants of Very Slow, Tight-Binding Competitive Inhibitors by Numerical Solution of Differential Equations, Independently of Precise Knowledge of the Enzyme Concentration

By Plesner I.W.   Bülow A.   Bols M.  

Analytical Biochemistry, Vol. 295, Iss. 2, 2001-08 ,pp. : 186-193

Elsevier

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A Scintillation Proximity Assay for the Raf/MEK/ERK Kinase Cascade: High-Throughput Screening and Identification of Selective Enzyme Inhibitors

By McDonald O.B.   Chen W.J.   Ellis B.   Hoffman C.   Overton L.   Rink M.   Smith A.   Marshalland C.J.   Wood E.R.  

Analytical Biochemistry, Vol. 268, Iss. 2, 1999-03 ,pp. : 318-329

Elsevier

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Thymidine phosphorylase from Escherichia coli : Tight-binding inhibitors as enzyme active-site titrants

By Gbaj Abdul   Edwards Philip N.   Reigan Philip   Freeman Sally   Jaffar Mohammed   Douglas Kenneth T.  

Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 21, Iss. 1, 2006-02 ,pp. : 69-73

Informa Healthcare

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High-Throughput Nonradioisotopic Determination of Binding of Platelet-Derived Growth Factor to Platelet-Derived Growth Factor Receptor β–Extracellular Domain Using Biotinylated Ligand with Enzyme-Linked Immunosorbent Assay

By Mahoney C.W.  

Analytical Biochemistry, Vol. 276, Iss. 1, 1999-12 ,pp. : 106-108

Elsevier

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