Endolymphatic hydrops revealed by intravenous gadolinium injection in patients with Ménière's disease

Author： Nakashima Tsutomu Naganawa Shinji Teranishi Masaaki Tagaya Mitsuhiko Nakata Seiichi Sone Michihiko Otake Hironao Kato Ken Iwata Tomoyuki Nishio Naoki

Publisher： Informa Healthcare

ISSN： 0001-6489

Source： Acta Oto-Laryngologica, Vol.130, Iss.3, 2010-03, pp. : 338-343

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

AbstractConclusion: Visualization of endolymphatic hydrops became possible after intravenous gadolinium (Gd) injection in patients with Ménière's disease. Objective: To visualize endolymphatic hydrops after intravenous Gd injection. Methods: Gd (gadoteridol; 0.2 mmol/kg) was injected intravenously in three patients with unilateral Ménière's disease. We performed three-dimensional fluid attenuated inversion recovery (3D-FLAIR) and three-dimensional real inversion recovery (3D-real IR) magnetic resonance imaging (MRI) 4 h after the injection using a 3-Tesla MRI unit. We used a 32-channel array coil to obtain a high signal-to-noise ratio. Results: Endolymphatic hydrops was observed in the ears of patients with Ménière's disease. However, Gd concentration in the perilymph was lower compared with that obtained after intratympanic Gd injection.