Interaction of Topotecan, DNA Topoisomerase I Inhibitor, with Double-Stranded Polydeoxyribonucleotides. 5. Topotecan is Capable of Producing Single- and Double-Strand Breaks in Circular Supercoiled DNA in the Absence of the Enzyme

Author: Grokhovsky S. L.   Strel'tsov S. A.   Zhuze A. L.  

Publisher: MAIK Nauka/Interperiodica

ISSN: 0026-8933

Source: Molecular Biology, Vol.37, Iss.6, 2003-11, pp. : 888-896

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Abstract