Author: Il'nitskaya S. I. Vasileva E. D. Kropachev K. Yu. Kaledin V. I.
Publisher: Springer Publishing Company
ISSN: 0007-4888
Source: Bulletin of Experimental Biology and Medicine, Vol.137, Iss.6, 2004-06, pp. : 548-550
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Abstract
Suckling mice were more sensitive to the hepatocarcinogenic effect of various carcinogens compared to adult animals. After treatment with o-aminoazotoluene and diethylnitrosamine HNF3-DNA-binding capacity and glucocorticoid-induced liver tyrosine aminotransferase activity in suckling mice decreased more significantly than in adult animals.