Acute electroretinographic changes during Sildenafil (Viagra) treatment for erectile dysfunction*

Author: Gabrieli C.B.   Regine F.   Vingolo E.M.   Rispoli E.   Isidori A.  

Publisher: Springer Publishing Company

ISSN: 0012-4486

Source: Documenta Ophthalmologica, Vol.107, Iss.2, 2003-09, pp. : 111-114

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Abstract

The authors describe their findings on 12 subjects who were treated with 50 mg of Sildenafil (Viagra) and underwent ERG measurements prior to and 1 hour after ingestion. The Naka–Rushton equation was used to describe the b-wave luminance-response function of the scotopic ERG. Statistically significant differences were noted in the Vmax and K values. Sildenafil ingestion resulted in an increase in Vmax (higher rod response to light stimuli) and a decrease in K (higher sensitivity).