Rhupus arthropathy in childhood-onset systemic-lupus erythematosus

Author： Saha Abhijeet Dubey Nand Kishore Kapoor Kanika Batra Vinita

ISSN： 1758-4272

Source： International Journal of Clinical Rheumatology, Vol.8, Iss.6, 2013-12, pp. : 623-625

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

This case report describes ruphus arthropathy in a 13-year-old girl with systemic lupus erythematosus. A detailed case description is given, together with laboratory results. Subcutaneous nodules were present on distal interphalangeal joints of the hands and fixed flexion deformity was present at metacarpophalangeal, proximal interphalangeal and distal interphalangeal joints of the fifth digit. Anticyclic citrullinated peptide antibody (antibodies against cyclic citrullinated peptides) titers were 79 U/ml (normal: 5 U/ml), a specific marker for rheumatoid arthritis. Renal biopsy was confirmatory of lupus nephritis. A diagnosis of childhood-onset systemic lupus erythematosus was made according to the modified ACR criteria. Clinicians need to be careful in monitoring the serious manifestations of the disease in childhood-onset lupus patients with rhupus arthropathy, and consider the poor response to standard disease-modifying agents.