Correction of Permeability with Pore Radius of Tight Junctions in Caco-2 Monolayers Improves the Prediction of the Dose Fraction of Hydrophilic Drugs Absorbed by Humans

Author： Saitoh Ryoichi   Sugano Kiyohiko   Takata Noriyuki   Tachibana Tatsuhiko   Higashida Atsuko   Nabuchi Yoshiaki   Aso Yoshinori  

Publisher： Springer Publishing Company

ISSN： 0724-8741

Source： Pharmaceutical Research, Vol.21, Iss.5, 2004-05, pp. : 749-755

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