Application of Clinical Trial Simulation to Compare Proof-of-Concept Study Designs for Drugs with a Slow Onset of Effect; An Example in Alzheimer's Disease

Author： Lockwood Peter   Ewy Wayne   Hermann David   Holford Nick  

Publisher： Springer Publishing Company

ISSN： 0724-8741

Source： Pharmaceutical Research, Vol.23, Iss.9, 2006-09, pp. : 2050-2059

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