Investigation of the Mechanism of Clearance of AMG 386, a Selective Angiopoietin-1/2 Neutralizing Peptibody, in Splenectomized, Nephrectomized, and FcRn Knockout Rodent Models

Author: Wu Benjamin   Johnson Jessica   Soto Marcus   Ponce Manuel   Calamba Dominador   Sun Yu-Nien  

Publisher: Springer Publishing Company

ISSN: 0724-8741

Source: Pharmaceutical Research, Vol.29, Iss.4, 2012-04, pp. : 1057-1065

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Abstract