Author: Declercq Heidi Ridder Leo Cornelissen Maria
Publisher: Springer Publishing Company
ISSN: 0920-9069
Source: Cytotechnology, Vol.49, Iss.1, 2005-09, pp. : 39-50
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Abstract
Selection of appropriate cultures having an osteogenic potential is a necessity if cell/biomaterial interactions are studied in long-term cultures. Osteoblastic cells derived from rat long bones or calvaria have the disadvantage of being in an advanced differentiation stage which results in terminal differentiation within 21 days. In this regard, less differentiated periosteum-derived osteoprogenitors could be more suitable.Periosteum-derived cells were isolated from the tibiae of adult Wistar rats (
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