Solid phase synthesis of benzamidine-derived sulfonamide libraries

Author: Kim S.W.   Hong C.Y.   Koh J.S.   Lee E.J.   Lee K.  

Publisher: Springer Publishing Company

ISSN: 1381-1991

Source: Molecular Diversity, Vol.3, Iss.2, 1998-02, pp. : 133-136

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Abstract

Using solid phase synthesis, a library has been constructed of benzamidine-derived sulfonamides which have strong inhibitory activity against blood coagulant thrombin. The library compounds were obtained in good yield and high purity.

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